| Type | Description |
|---|---|
| Definition | mitochondrial transcription termination factor 4 |
| Date | Results | Publications |
|---|---|---|
| 2017-06-10 10:58:00 | The overexpression of MTERF4 induced a significant increase in the levels of APP protein and secreted Abeta 42 in HEK293-APPswe cells compared with control cells these results suggest that MTERF4 promotes the amyloidogenic processing of APP by inhibiting ADAM10 in HEK293-APPswe cells; therefore, MTERF4 may play an important role in the pathogenesis of Alzheimer's disease. | 27894840 |
| 2014-02-26 18:02:00 | analysis of the 3D crystal structure of the human MTERF4-NSUN4 complex | 22949673 |
| Type | IDs |
|---|---|
| Synonymous | MTERFD2 |
| Gene |
UniProtKB-ID:
MTEF4_HUMAN,
B4DFP7_HUMAN
UniprotKB:
Q7Z6M4,
B4DFP7
UniParc:
UPI000173A62B,
UPI0000209875
EMBL:
AC005237,
BC053533,
AK291665,
AF161359,
AK294192
Ensembl:
ENSG00000122085
KO:
hsa:130916
|
| Nucleutide sequences |
EMBL-CDS:
AAH53533.2,
AAF28919.1,
BAF84354.1,
BAG57508.1
Gene_ORFName:
HSPC096
Ensembl_TRS:
ENST00000241527,
ENST00000614476,
ENST00000391980,
ENST00000406593
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000241527,
ENSP00000480378,
ENSP00000375840,
ENSP00000384998
RefSeq:
XP_016858872.1,
XP_016858876.1,
XP_024308474.1,
NP_872307.2,
XP_016858869.1,
XP_024308477.1,
XP_024308476.1,
NP_001317109.1,
XP_006712355.1,
XP_016858880.1,
XP_016858868.1,
NP_001317108.1,
XP_016858870.1,
XP_024308475.1,
XP_016858871.1
|
| Others |
UniRef100:
UniRef100_B4DFP7,
UniRef100_Q7Z6M4
UniRef90:
UniRef90_Q7Z6M4
UniRef50:
UniRef50_Q7Z6M4
UniGene:
Hs.159556
CCDS:
CCDS2544.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员