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13088 Cyp2b10

13088

Cyp2b10

cytochrome P450, family 2, subfamily b, polypeptide 10

protein-coding

Mus musculus

基因描述

Type Description
Definition cytochrome P450, family 2, subfamily b, polypeptide 10

研究结论

Date Results Publications
2020-11-21 13:11:00 Cyp2b-null male mice are susceptible to diet-induced obesity and perturbations in lipid homeostasis. 31202118
2017-05-27 10:14:00 results from the present study demonstrate a novel regulatory role of PPARbeta/delta in modulating CYP2B10 that may contribute to the etiology of alcoholic liver disease. 27765815
2015-06-20 10:18:00 Study demonstrated that in mouse livers,the redox-sensitive transcription factor Nrf2 is involved in the gene expression of Cyp2b10 and Cyp2a5. 24494203
2013-12-14 10:34:00 Studies indicate that phenobarbital binding to EGFR inhibits distal signaling to derepress RACK1-facilitated dephosphorylation of constitutive active androstane receptor (CAR) by PP2A, and activates the transcription of Cyp2B10. 23652202
2012-10-27 10:35:00 expression of Cyp2b10 was induced in both WT and PXR-/- hypothyroid mice, and this induction was abolished in CAR-/- mice and in and CAR-/- PXR-/- double knockouts 22503787

名称对应

Type IDs
Synonymous Cyp2b, Cyp2b20, p16
Gene
UniProtKB-ID: Q9WUD0_MOUSE
UniprotKB: Q9WUD0
UniParc: UPI00000E88AF
EMBL: AK028103, AC160471, AF128849, BC060973
Ensembl: ENSMUSG00000030483
KO: mmu:13088
Nucleutide sequences
EMBL-CDS: BAC25748.1, AAH60973.1, AAD28466.1
Ensembl_TRS: ENSMUST00000072438
Protein sequencees
Ensembl_PRO: ENSMUSP00000072264
RefSeq: NP_034129.1
Others
UniRef100: UniRef100_Q9WUD0
UniRef90: UniRef90_P00176
UniRef50: UniRef50_P00176
UniGene: Mm.218749

全选

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研究热度

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