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13082 Cyp26a1

13082

Cyp26a1

cytochrome P450, family 26, subfamily a, polypeptide 1

protein-coding

Mus musculus

基因描述

Type Description
Definition cytochrome P450, family 26, subfamily a, polypeptide 1

研究结论

Date Results Publications
2020-04-04 10:38:00 findings demonstrate that despite lacking a major impact on endogenous all-trans-retinoic acid (atRA) signaling, Cyp26a1 critically contributes as a barrier for exogenous atRA exposure 31167781
2019-12-07 11:44:00 Loss of Strap selectively induced Cyp26A1 expression in mouse EBs, suggesting a potential role of STRAP in RA signaling. 29781215
2019-08-31 11:32:00 We found that developing teeth from K14-CRE/Shhf/f mutant mice exhibit severe downregulation of Cyp26a1 and Cyp26c1 expression levels in the inner dental epithelium 31072004
2017-08-12 11:52:00 These findings provide a new line of evidence correlating the deleterious effects of blocking CYP26A1 in pregnancy with the aberrant regulation of NK cells in the uterus. 27860312
2017-06-24 10:27:00 Cyp26a1, which encodes a key enzyme for catabolic inactivation of retinoic acid (RA) required for tight control of local RA concentrations, is significantly downregulated in embryos of diabetic mice. Embryonic tissues expressing Cyp26a1 show reduced efficiency of RA clearance. 28087565

名称对应

Type IDs
Synonymous Cyp26, P450RA, P450RAI, RAH
Gene
UniProtKB-ID: CP26A_MOUSE, A0A0R4J061_MOUSE
UniprotKB: O55127, A0A0R4J061
UniParc: UPI0000027AD2, UPI00000224D6
EMBL: BC012673, AF115769, AC110212, Y12657
Ensembl: ENSMUSG00000024987
KO: mmu:13082
Nucleutide sequences
EMBL-CDS: AAD17217.1, AAH12673.1, CAA73206.1
Ensembl_TRS: ENSMUST00000025946
Protein sequencees
Ensembl_PRO: ENSMUSP00000025946
RefSeq: XP_017173542.1, NP_031837.2
Others
UniRef100: UniRef100_O55127, UniRef100_A0A0R4J061
UniRef90: UniRef90_O55127
UniRef50: UniRef50_P79739
UniGene: Mm.42230
CCDS: CCDS29780.1

全选

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