| Type | Description |
|---|---|
| Definition | cytochrome P450, family 21, subfamily a, polypeptide 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-04-06 11:44:00 | To test this hypothesis, we administered intravenously an AAV serotype rh.10 gene transfer vector (AAVrh.10-21OH-HA) to 21-hydroxylase deficient mice (21OH(-/-)). The data demonstrates that a single intravenous administration efficiently transduces adrenocortical cells leading to 21OH-HA expression and restoration of normal steroidogenesis. | 29316814 |
| 2017-07-08 10:08:00 | Cyp21a1 remains expressed in the most distal structure of the developing lung even though these structures are changing, but its expression is not restricted to these areas. | 28216153 |
| 2017-02-18 10:24:00 | Extra-adrenal induction of Cyp21a1 ameliorates steroid metabolism in 21-OHD mice. This study suggests a novel therapeutic strategy for congenital adrenal hyperplasia, which warrants further investigations. | 27432820 |
| 2012-03-10 10:25:00 | Ureteral obstruction leads to the alteration of renal vitamin D metabolic enzyme expression and calcium transporter abundance, which may secondarily induce the abnormality of vitamin D endocrine system and bone health. | 22029643 |
| 2010-09-20 12:16:00 | Allelic variability for 30-kb deletion in patients with 21-hydroxylase deficiency indicates that a founder effect may be improbable for most monomodular alleles carrying CYP21A1P/A2 chimeric genes in Brazil | 20587039 |
| Type | IDs |
|---|---|
| Synonymous | 21-OH, 21OH, 21OHA, 21OHB, CYP21OH-A, Cyp21, Cyp21-ps1, Cyp21B, Cyp21a2-ps, Cyp21a2ps, Oh21-1, Oh21-2 |
| Gene |
UniProtKB-ID:
CP21A_MOUSE,
Q3UJ92_MOUSE,
A0A0R4J048_MOUSE
UniprotKB:
P03940,
Q3UJ92,
A0A0R4J048
UniParc:
UPI00000E8397,
UPI00000E624B,
UPI00005AC57E
EMBL:
CT025759,
AF049850,
AK146565,
M15009,
M64933,
BC127167,
AB015623
Ensembl:
ENSMUSG00000024365
KO:
mmu:13079
|
| Nucleutide sequences |
EMBL-CDS:
AAI27168.1,
AAA40118.1,
AAC05278.1,
AAA37114.1,
BAA31153.1,
BAE27263.1
Ensembl_TRS:
ENSMUST00000025223
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000025223
RefSeq:
NP_034125.2
|
| Others |
UniRef100:
UniRef100_P03940,
UniRef100_Q3UJ92,
UniRef100_A0A0R4J048
UniRef90:
UniRef90_P03940
UniRef50:
UniRef50_P08686
UniGene:
Mm.440407
CCDS:
CCDS28658.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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