| Type | Description |
|---|---|
| Definition | cytochrome P450, family 17, subfamily a, polypeptide 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 13:00:00 | CYP17A1 deficient XY mice display susceptibility to atherosclerosis, altered lipidomic profile and atypical sex development. | 32472014 |
| 2020-02-15 10:54:00 | spinal P450c17 activates astrocytes via p38 phosphorylation. | 31387001 |
| 2017-11-18 10:29:00 | through mouse-to-human search and validation, we found that CYP17A1 is overexpressed in hepatocellular carcinomas and it has great potentiality as a noninvasive marker for hepatocellular carcinoma detection | 27339169 |
| 2016-12-24 10:38:00 | Demonstration of the physiologic importance of cytochrome b5 activating the 17,20-lyase reaction and the production of 19-carbon sex steroids from 21-carbon precursors in mice. | 26974035 |
| 2015-01-24 13:12:00 | TRalpha/T3 directly acts on the P450c17 promoter, which contains putative thyroid response elements, and indirectly acts on the promoter of steroidogenic enzyme genes by modulating Nur77 transactivation on these promoters. | 24725081 |
| Type | IDs |
|---|---|
| Synonymous | Cyp17, p450c17 |
| Gene |
UniProtKB-ID:
CP17A_MOUSE,
Q53YJ1_MOUSE,
Q3UYU1_MOUSE
UniprotKB:
P27786,
Q53YJ1,
Q3UYU1
UniParc:
UPI00000224FF,
UPI00005ABA8C
EMBL:
AK134376,
AY594330,
M64863
Ensembl:
ENSMUSG00000003555
KO:
mmu:13074
|
| Nucleutide sequences |
EMBL-CDS:
AAA39877.1,
AAT01928.1,
BAE22120.1
Ensembl_TRS:
ENSMUST00000026012
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000026012
RefSeq:
NP_031835.3
|
| Others |
UniRef100:
UniRef100_P27786,
UniRef100_Q3UYU1
UniRef90:
UniRef90_P27786
UniRef50:
UniRef50_P05093
UniGene:
Mm.1262
CCDS:
CCDS29882.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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