| Type | Description |
|---|---|
| Definition | zinc finger AN1-type containing 2B |
| Date | Results | Publications |
|---|---|---|
| 2016-09-17 12:04:00 | Results demonstrate that on specific translocation inhibition, a p97-AIRAPL complex directly binds and regulates the efficient processing of polyubiquitinated pQC substrates by the UPS. Results also demonstrate p97's role in pQC processing of preproinsulin in cases of naturally occurring mutations within the signal sequence of insulin. | 26337389 |
| 2016-05-28 10:47:00 | Consistent with its proposed role as a tumor suppressor of myeloid transformation, AIRAPL expression is widely abrogated in human myeloproliferative disorders. | 26692333 |
| 2014-12-20 10:16:00 | Zinc finger proteins may be associated with pathophysiology of severe dry eye syndrome. | 24215362 |
| 2014-03-01 10:09:00 | AIRAPL binds to p97 and forms a complex in the endoplasmic reticulum membrane. | 24160817 |
| 2010-01-21 00:00:00 | An AIP-1 human homologue, ZFAND2B, has a similar protective effect against Abeta toxicity. | 19414486 |
| Type | IDs |
|---|---|
| Synonymous | AIRAPL |
| Gene |
UniProtKB-ID:
ZFN2B_HUMAN,
A0A087X0D9_HUMAN
UniprotKB:
Q8WV99,
A0A087X0D9
UniParc:
UPI00027CD721,
UPI000004CC12,
UPI00000735B5
EMBL:
BC018415,
AK091345,
AC068946
Ensembl:
ENSG00000158552
KO:
hsa:130617
|
| Nucleutide sequences |
EMBL-CDS:
BAC03642.1,
AAH18415.1
Ensembl_TRS:
ENST00000289528,
ENST00000409594,
ENST00000409336,
ENST00000409206,
ENST00000444522,
ENST00000621130
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000386824,
ENSP00000289528,
ENSP00000386898,
ENSP00000411334,
ENSP00000386399,
ENSP00000483320
RefSeq:
NP_001257928.1,
XP_006712348.1,
XP_016858857.1,
XP_006712349.1,
NP_620157.1,
NP_001257927.1
|
| Others |
UniRef100:
UniRef100_A0A087X0D9,
UniRef100_Q8WV99
UniRef90:
UniRef90_Q8WV99,
UniRef90_Q91X58
UniRef50:
UniRef50_Q91X58,
UniRef50_Q8WV99
UniGene:
Hs.534540
CCDS:
CCDS2435.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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