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13046 Celf1

13046

Celf1

CUGBP, Elav-like family member 1

protein-coding

Mus musculus

基因描述

Type Description
Definition CUGBP, Elav-like family member 1

研究结论

Date Results Publications
2020-10-31 13:17:00 The cataract-linked RNA-binding protein Celf1 post-transcriptionally controls the spatiotemporal expression of the key homeodomain transcription factors Pax6 and Prox1 in lens development. 32594240
2020-08-01 12:02:00 RNA-seq analysis of mouse neocortical polysomes demonstrated that the translation of distinct mRNA isoforms of the RNA binding protein (RBP), Elavl4, in radial glia progenitors and early neurons depends on its alternative Elavl4 isoform-specific translation depends on upstream control by another RBP, Celf1. Celf1 regulation of Elavl4 translation dictates development of glutamatergic neurons. 32245946
2020-01-18 11:19:00 miR-206 helped rescue myogenic deficiency by inhibiting CUGBP1 accumulation in cell models of myotonic dystrophy. These data suggest that increased miR-206 levels in myoblasts may lead to better skeletal muscle differentiation. 30281408
2019-01-19 11:50:00 These results indicate that CELF1 target RNAs are aberrantly spliced in the Type 1 diabetic heart leading to abnormal gene expression. 30158053
2018-05-26 12:03:00 this study shows that the absence of Celf1 causes neonatal cardiac dysfunction and transcriptome changes 27759042

名称对应

Type IDs
Synonymous 1600010O03Rik, AA407467, Brunol2, CUG-BP, CUG-BP1, CUGBP, Cugbp1, D2Wsu101e, HNAB50, NAB50
Gene
UniProtKB-ID: CELF1_MOUSE
UniprotKB: P28659
UniParc: UPI00000019A4, UPI00001EF485, UPI000002A791, UPI000002A792
EMBL: AK135030, AK143698, AL672241, AK014492, AF267535, AK156725, X61451, BC021393, AJ007987, AF314172, AB050499
Ensembl: ENSMUSG00000005506, ENSMUSG00000110883
KO: mmu:13046
Nucleutide sequences
EMBL-CDS: BAE25504.1, AAK00297.1, BAE33820.1, CAC20707.1, BAB29392.1, BAB87831.1, BAE22391.1, CAA43691.1, AAF78957.1
Ensembl_TRS: ENSMUST00000214114, ENSMUST00000213174, ENSMUST00000111448, ENSMUST00000111455, ENSMUST00000177642, ENSMUST00000215738, ENSMUST00000217268, ENSMUST00000215997, ENSMUST00000068747, ENSMUST00000111452, ENSMUST00000214684, ENSMUST00000111449, ENSMUST00000005643, ENSMUST00000216171, ENSMUST00000111451, ENSMUST00000213209
Protein sequencees
Ensembl_PRO: ENSMUSP00000107078, ENSMUSP00000107079, ENSMUSP00000107075, ENSMUSP00000149376, ENSMUSP00000005643, ENSMUSP00000150050, ENSMUSP00000136109, ENSMUSP00000107076, ENSMUSP00000150191, ENSMUSP00000149473, ENSMUSP00000149154, ENSMUSP00000150186, ENSMUSP00000070438, ENSMUSP00000150227, ENSMUSP00000107082, ENSMUSP00000149393
RefSeq: XP_030102962.1, XP_030102983.1, XP_030102944.1, XP_030102954.1, XP_036013939.1, XP_030102972.1, XP_030102970.1, XP_030102979.1, XP_036013924.1, NP_001231820.1, XP_030102943.1, XP_030102971.1, XP_030102978.1, XP_036013919.1, XP_030102969.1, XP_036013927.1, XP_030102974.1, XP_006498732.1, NP_941955.1, XP_036013909.1, XP_036013922.1, XP_017170784.1, NP_001231832.1, XP_036013941.1, NP_059064.2, XP_030102946.1, XP_036013942.1, XP_030102975.1, XP_036013932.1, XP_030102961.1, XP_030102966.1
Others
UniRef100: UniRef100_P28659
UniRef90: UniRef90_Q92879
UniRef50: UniRef50_Q92879
UniGene: Mm.29495, Mm.490161
CCDS: CCDS16420.1, CCDS16421.1

全选

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研究热度

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