| Type | Description |
|---|---|
| Definition | cortactin |
| Date | Results | Publications |
|---|---|---|
| 2020-08-22 15:30:00 | Actin-Binding Protein Cortactin Promotes Pathogenesis of Experimental Autoimmune Encephalomyelitis by Supporting Leukocyte Infiltration into the | 31911458 |
| 2020-02-29 10:47:00 | Autism candidate gene DIP2A regulates spine morphogenesis via acetylation of cortactin. | 31600191 |
| 2018-06-23 11:40:00 | this paper shows that cortactin deficiency causes increased RhoA/ROCK1-dependent actomyosin contractility, intestinal epithelial barrier dysfunction, and disproportionately severe dextran sulfate sodium-induced colitis | 28120846 |
| 2018-05-19 12:00:00 | Secretion of the barrier-stabilising hormone adrenomedullin, which activates Rap1 and counteracts actomyosin contractility, was reduced in plasma from cortactin-deficient mice. Cortactin plays a role in controlling actomyosin contractility with consequences for endothelial barrier integrity. | 27357373 |
| 2017-12-23 11:03:00 | These findings suggest that the patterning of podosomes into a sealing zone involves the dynamic interaction between cofilin, CTTN, and the microtubule + ends. | 27064822 |
| Type | IDs |
|---|---|
| Synonymous | 1110020L01Rik, Ems1 |
| Gene |
UniProtKB-ID:
SRC8_MOUSE,
Q8BNA5_MOUSE,
Q921L6_MOUSE
UniprotKB:
Q60598,
Q8BNA5,
Q921L6
UniParc:
UPI00000EB222,
UPI0000023693,
UPI0000023692
EMBL:
AK084249,
BC011434,
CH466531,
AK168945,
U03184,
AC140268,
AK148010,
AK165555,
AK146856,
AK168699
Ensembl:
ENSMUSG00000031078
KO:
mmu:13043
|
| Nucleutide sequences |
EMBL-CDS:
EDL18251.1,
AAA19689.1,
BAE27485.1,
BAE40543.1,
BAE28287.1,
BAC39148.1,
AAH11434.1,
BAE40752.1,
BAE38252.1
Ensembl_TRS:
ENSMUST00000103079,
ENSMUST00000033407
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000099368,
ENSMUSP00000033407
RefSeq:
NP_001239501.1,
NP_001344045.1,
NP_031829.2
|
| Others |
UniRef100:
UniRef100_Q921L6,
UniRef100_Q8BNA5,
UniRef100_Q60598
UniRef90:
UniRef90_Q60598
UniRef50:
UniRef50_Q60598
UniGene:
Mm.205601,
Mm.490123
CCDS:
CCDS22049.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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