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13017 Ctbp2

13017

Ctbp2

C-terminal binding protein 2

protein-coding

Mus musculus

基因描述

Type Description
Definition C-terminal binding protein 2

研究结论

Date Results Publications
2021-01-02 12:50:00 The corepressor CtBP2 is required for proper development of the mouse cerebral cortex. 32169478
2020-05-02 10:21:00 MCRIP1 interferes with interactions of CtBP with the lung-enriched transcriptional repressors, Foxp1 and Foxp2, thereby preventing the recruitment of the CtBP co-repressor complex to the SP-B and SP-C promoters and maintaining them in an active chromatin state. Homozygous deficiency of Mcrip1 in mice causes fatal respiratory distress due to abnormal transcriptional repression of surfactant proteins. 31240265
2019-06-01 10:04:00 VGLL4 acted as an adaptor protein that enhanced the interaction between TEAD4 and CtBP2, and this TEAD4-VGLL4-CtBP2 ternary complex dynamically existed at the early stage of adipogenesis. 30209132
2018-09-01 11:25:00 The authors postulate that RIBEYE disruption is partially compensated by several small active zone organization at each synaptic contact between inner hair cells and spiral ganglion neurons. 29328020
2018-06-09 11:41:00 These findings suggest a suppressive function for Ctbp2 in reducing the protein level of beta-catenin, along with priming its position on core pluripotency genes to hinder beta-catenin deposition, which is central to commitment to the appropriate lineage. 29026198

名称对应

Type IDs
Synonymous AA407280, D7Ertd45e, Gtrgeo6, Ribeye
Gene
UniProtKB-ID: CTBP2_MOUSE, Q91YZ2_MOUSE, Q3UGL5_MOUSE
UniprotKB: P56546, Q91YZ2, Q3UGL5
UniParc: UPI000024DF79, UPI00000E7F3D, UPI000002364F
EMBL: BC017520, BC013333, AK147871, AK134399, AC119806, AF016508, AB033123, AC138624, AF059735
Ensembl: ENSMUSG00000030970
KO: mmu:13017
Nucleutide sequences
EMBL-CDS: BAA85181.1, AAC40043.1, AAC33873.1, AAH17520.1, BAE22127.1, AAH13333.1, BAE28193.1
Ensembl_TRS: ENSMUST00000169570, ENSMUST00000033269, ENSMUST00000166439
Protein sequencees
Ensembl_PRO: ENSMUSP00000130294, ENSMUSP00000033269, ENSMUSP00000127448
RefSeq: XP_030097925.1, XP_006507373.1, XP_030097928.1, XP_006507372.1, NP_034110.1, XP_030097926.1, XP_030097930.1, XP_006507374.1, XP_030097929.1, NP_001334552.1, XP_006507371.1, XP_006507375.1, XP_030097924.1, XP_036008524.1, XP_030097927.1, XP_036008523.1, NP_001164215.1
Others
UniRef100: UniRef100_Q91YZ2, UniRef100_P56546
UniRef90: UniRef90_Q91YZ2, UniRef90_P56545
UniRef50: UniRef50_P56545, UniRef50_P56546-2
UniGene: Mm.246240, Mm.389984
CCDS: CCDS52417.1, CCDS21930.1

全选

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