| Type | Description |
|---|---|
| Definition | cystatin B |
| Date | Results | Publications |
|---|---|---|
| 2017-10-07 12:47:00 | The data of this study show that CXCL13 expression is a hallmark of microglial activation in Cstb (-/-) mice and that the brain inflammation is linked to peripheral inflammatory changes, which might contribute to the disease pathology of progressive myoclonus epilepsy.. | 27894304 |
| 2017-07-29 12:52:00 | CSTB has a role in chemotaxis, antigen-presentation, and in immune- and defense response-associated processes by altering pathway signaling | 27355630 |
| 2017-01-28 10:32:00 | Deletion of the encoding Cstb gene in Npc1-deficient mice resulted in striking deleterious effects, particularly within the cerebellum where diffuse loss of Purkinje cells was observed in young mice. This may be a consequence of damage to lysosomal membranes by reactive oxygen species leading to the leakage of lysosomal contents that culminates in apoptosis. | 26908626 |
| 2015-09-26 15:04:00 | Results suggest a role for CSTB in regulating microglial activation: data link CSTB deficiency to early activation and altered functional properties of microglia, imply presence of both enhanced and suppressed immune response-related microglial functions | 25327891 |
| 2015-01-24 11:52:00 | the LPS-induced sepsis in StB KO mice is dependent on caspase-11 and mitochondrial reactive oxygen species but is not associated with the lysosomal destabilization and increased cathepsin activity in the cytosol | 25288807 |
| Type | IDs |
|---|---|
| Synonymous | AA960480, Stfb |
| Gene |
UniProtKB-ID:
CYTB_MOUSE
UniprotKB:
Q62426
UniParc:
UPI0000003E42
EMBL:
AK002403,
BC056170,
U59807,
AK151205
Ensembl:
ENSMUSG00000005054
KO:
mmu:13014
|
| Nucleutide sequences |
EMBL-CDS:
BAB22074.1,
AAH56170.1,
AAC52851.1,
BAE30202.1
Ensembl_TRS:
ENSMUST00000005185
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000005185
RefSeq:
NP_031819.1
|
| Others |
UniRef100:
UniRef100_Q62426
UniRef90:
UniRef90_Q62426
UniRef50:
UniRef50_Q62426
UniGene:
Mm.6095
CCDS:
CCDS23964.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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