| Type | Description |
|---|---|
| Definition | cystatin C |
| Date | Results | Publications |
|---|---|---|
| 2020-04-25 11:44:00 | cystatin C promoted skewing of T cells toward proinflammatory T-helper (Th)1/Th17 differentiation which was mediated by augmented extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase phosphorylation. | 31513306 |
| 2019-11-30 12:17:00 | In mouse and human lungs with interstitial fibrosis, CST3 and GDF15 expression levels were markedly reduced, and the restoration of these cytokines alleviated the fibrotic changes in mouse lungs. | 29724997 |
| 2017-07-01 11:58:00 | CysC plays an important regulatory role in combating cell death via the autophagic pathway in atherosclerosis. | 27079462 |
| 2016-05-14 10:57:00 | Data (including data from studies in mutant mice) suggest that up-regulation of Cst3, as observed in plasma of mice with type 2 diabetes, down-regulates insulin signaling and promotes endoplasmic reticulum stress in hepatocytes but not in myotubes. | 26592151 |
| 2016-04-30 11:18:00 | Cystatin C is a potential pathogenic signal triggering neurodegeneration in multiple system atrophy. | 24405769 |
| Type | IDs |
|---|---|
| Synonymous | CysC |
| Gene |
UniProtKB-ID:
CYTC_MOUSE
UniprotKB:
P21460
UniParc:
UPI0000003E44
EMBL:
AK131728,
AK166430,
M59470,
AK151160,
AK002438,
AK161856,
AF483487,
AK013676,
U10098,
BC002072,
AK014368,
AF483486,
AK146333
Ensembl:
ENSMUSG00000027447
KO:
mmu:13010
|
| Nucleutide sequences |
EMBL-CDS:
BAE38771.1,
AAL90760.1,
BAE20785.1,
BAB29303.1,
AAA63298.1,
AAL90761.1,
AAB41056.1,
BAE30165.1,
AAH02072.1,
BAE36608.1,
BAB22101.1,
BAE27088.1,
BAB28949.1
Ensembl_TRS:
ENSMUST00000028938
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000028938
RefSeq:
NP_034106.2
|
| Others |
UniRef100:
UniRef100_P21460
UniRef90:
UniRef90_P21460
UniRef50:
UniRef50_P14841
UniGene:
Mm.4263
CCDS:
CCDS16852.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员