| Type | Description |
|---|---|
| Definition | DnaJ heat shock protein family (Hsp40) member C5 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-25 11:37:00 | Point mutations in cysteine string protein-alpha (CSP alpha) cause dominantly inherited adult-onset neuronal ceroid lipofuscinosis (ANCL). Normally palmitoylated cysteine string region of cysteine string protein alpha loses palmitoylation in ANCL mutants. | 32042150 |
| 2020-03-28 11:53:00 | Studied role of the synaptic co-chaperone cysteine string protein-alpha in postnatal quiescence of mouse hippocampal radial glia-like (RGL) neural stem cells through mechanistic target of rapamycin kinase (mTOR) activation. | 30926666 |
| 2018-09-08 11:20:00 | Results indicate that by assisting local lysosome/proteasome processes, CSPalpha-mediated removal of toxic proteins via extracellular vesicles plays a central role in synaptic proteostasis. | 28424476 |
| 2017-09-30 10:07:00 | These data show that neurodegenerative processes associated with lysosomal dysfunction may be presynaptically initiated by a concomitant reduction in alpha-synuclein and CSPalpha levels at nerve terminals. | 27881461 |
| 2014-11-22 12:56:00 | CSPalpha has a role in regulating synaptic excitability and neurotransmission by limiting expression of BK channels. | 24475152 |
| Type | IDs |
|---|---|
| Synonymous | 2610314I24Rik, AU018536, Csp |
| Gene |
UniProtKB-ID:
DNJC5_MOUSE
UniprotKB:
P60904
UniParc:
UPI0000000D0C
EMBL:
AK032373,
AF032115,
AK029006
Ensembl:
ENSMUSG00000000826
KO:
mmu:13002
|
| Nucleutide sequences |
EMBL-CDS:
BAC27841.1,
AAB87080.1,
BAC26236.1
Ensembl_TRS:
ENSMUST00000108796,
ENSMUST00000108797,
ENSMUST00000072334
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000072175,
ENSMUSP00000104424,
ENSMUSP00000104425
RefSeq:
XP_036013878.1,
NP_001258514.1,
XP_011238225.1,
NP_058055.1,
NP_001258513.1
|
| Others |
UniRef100:
UniRef100_P60904
UniRef90:
UniRef90_P60904
UniRef50:
UniRef50_Q9H3Z4
UniGene:
Mm.140761,
Mm.391807,
Mm.491282
CCDS:
CCDS17215.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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