| Type | Description |
|---|---|
| Definition | casein kinase 2, alpha prime polypeptide |
| Date | Results | Publications |
|---|---|---|
| 2020-05-02 12:05:00 | Loss of lamin A in Lmna-knockout mouse embryonic fibroblasts (MEFs) confers increased CK2 activity. Conversely, prelamin A that accumulates in Zmpste24-deficent MEFs exhibits a high CK2alpha binding affinity and concomitantly reduces CK2 kinase activity | 30906869 |
| 2020-04-25 11:24:00 | Results show that CK2alpha' subunit has a primary role in GN11 neuronal cell adhesion and reducing migration properties of GN11 cells by activating the Akt-GSK3beta axis, whereas CK2alpha subunit is dispensable. | 31779225 |
| 2018-11-17 11:58:00 | Phosphosites notoriously generated by CK2 are not fully abrogated in CK2 alpha/alpha'((-/-)) cells, while some phosphosites unrelated to CK2 are significantly altered. CK2 promotes phosphoproteomics perturbations attributable to kinases other than CK2. | 29119230 |
| 2018-03-24 10:35:00 | We found that C/EBPbeta is phosphorylated by CK2 under AMPK suppression and ER stress, which are important from the viewpoint of the worsening pathological condition of type 2 diabetes, such as decreased insulin secretion and apoptosis of pancreatic beta cells/ | 29448105 |
| 2017-12-23 11:20:00 | Data (including data from studies using knockout mice) suggest that Brg1 is phosphorylated by casein kinase 2 (Ck2; Ck2alpha1 and Ck2alpha-prime are catalytic subunits) in proliferating skeletal myoblasts; Brg1 is catalytic subunit of SWI/SNF chromatin-remodeling enzymes; Ck2-mediated phosphorylation of Brg1 appears to regulate myoblast proliferation. (Brg1 = Brahma-related gene 1 protein) | 28939766 |
| Type | IDs |
|---|---|
| Synonymous | 1110035J23Rik, C77789, CK2 |
| Gene |
UniProtKB-ID:
CSK22_MOUSE,
Q545V8_MOUSE,
Q8CDH5_MOUSE
UniprotKB:
O54833,
Q545V8,
Q8CDH5
UniParc:
UPI0000003E63,
UPI00000E9249
EMBL:
AJ001420,
BC057862,
AK002927,
AK030035,
AF012251
Ensembl:
ENSMUSG00000046707
KO:
mmu:13000
|
| Nucleutide sequences |
EMBL-CDS:
CAA04753.1,
AAH57862.1,
AAC53552.1,
BAB22463.1,
BAC26752.1
Ensembl_TRS:
ENSMUST00000212214,
ENSMUST00000056919
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000055919,
ENSMUSP00000148404
RefSeq:
XP_006530704.1,
XP_030099139.1,
XP_006530706.1,
XP_036009638.1,
XP_006530705.1,
NP_034104.1,
XP_036009637.1
|
| Others |
UniRef100:
UniRef100_O54833
UniRef90:
UniRef90_P19784
UniRef50:
UniRef50_P19784
UniGene:
Mm.440348
CCDS:
CCDS22562.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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