| Type | Description |
|---|---|
| Definition | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
| Date | Results | Publications |
|---|---|---|
| 2020-05-09 10:29:00 | These data show that loss of membrane GM-CSFRalpha following GM-CSF exposure does not preclude sustained GM-CSF/GM-CSFRalpha signaling and that this receptor plays a key role in ligand clearance. Hence neutrophilic activation via GM-CSFR may play an important role in neutrophilic lung inflammation even in the absence of high GM-CSF levels or GM-CSFRalpha expression. | 30942918 |
| 2019-09-21 10:49:00 | we have demonstrated that CFP1 plays a crucial role in GM-CSF-derived macrophages, in which it positively regulates phagocytic and bactericidal activity mainly through promoting Csf2ralpha expression and the subsequent activation of downstream pathways. | 30154795 |
| 2018-06-02 12:07:00 | GM-CSF Ralpha blockade in relapsing-remitting experimental autoimmune encephalomyelitis prevented disease relapses and inhibited T cell responses specific for both the inducing and spread myelin peptides | 28641926 |
| 2017-09-09 10:13:00 | a STOP mutation in the GM-CSFRalpha chain, leading to a complete and specific deficiency in GM-CSF signaling, is reported. | 27468760 |
| 2012-06-30 10:26:00 | GM-CSFRalpha levels peaked between E13 and E15 in the brain. | 22103458 |
| Type | IDs |
|---|---|
| Synonymous | CD116, Csfgmra, GM-CSF-Ra, GM-CSFR |
| Gene |
UniProtKB-ID:
CSF2R_MOUSE
UniprotKB:
Q00941
UniParc:
UPI0000D8AD23
EMBL:
AC165327,
M85078
Ensembl:
ENSMUSG00000059326
KO:
mmu:12982
|
| Nucleutide sequences |
EMBL-CDS:
AAA37421.1
Ensembl_TRS:
ENSMUST00000076046,
ENSMUST00000237386
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000075423,
ENSMUSP00000158457
RefSeq:
XP_017173541.1,
XP_036017312.1,
XP_011245432.1,
XP_036017311.1,
XP_011245433.1,
NP_034100.2,
XP_036017313.1,
XP_011245434.1
|
| Others |
UniRef100:
UniRef100_Q00941
UniRef90:
UniRef90_Q00941
UniRef50:
UniRef50_Q00941
UniGene:
Mm.287228
CCDS:
CCDS29946.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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