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12974 Cs

12974

Cs

citrate synthase

protein-coding

Mus musculus

基因描述

Type Description
Definition citrate synthase

研究结论

Date Results Publications
2020-10-24 13:59:00 Extra-mitochondrial citrate synthase initiates calcium oscillation and suppresses age-dependent sperm dysfunction. 31857692
2015-07-04 13:28:00 The CS activity decreased in the infarcted tissue of wild-type (WT) mice at day 1 post-MI (p<0.05), but this was not observed in the MMP-9 null mice, suggesting that MMP-9 deletion helps to maintain the mitochondrial activity post-MI 24382150
2012-10-27 11:24:00 Multiple lines of evidence implicate this missense mutation (H55N) as the underlying cause of ahl4-related hearing loss, likely through its effects on mitochondrial adenosine trisphosphate (ATP) and free radical production in cochlear hair cells. 21803452
2011-04-23 10:42:00 H55N polymorphism in Cs could be the underlying cause of low CS activity and its high affinity for substrates in A/J mice compared with other strains. 20716647
2010-01-21 00:00:00 A high-fat diet increases adiposity but maintains mitochondrial oxidative enzymes without affecting development of heart failure with pressure overload. 19767529

名称对应

Type IDs
Synonymous 2610511A05Rik, 9030605P22Rik, Ahl4, BB234005, Cis
Gene
UniProtKB-ID: CISY_MOUSE
UniprotKB: Q9CZU6
UniParc: UPI00000277E4
EMBL: BC029754, AK167125, AK163273, AK145643, AB056479, BC013554, AK012151, AK149990, AK166814
Ensembl: ENSMUSG00000005683
KO: mmu:12974
Nucleutide sequences
EMBL-CDS: BAE37268.1, BAB28063.1, BAE26560.1, BAE39041.1, AAH13554.1, BAB63945.1, AAH29754.1, BAE39273.1, BAE29218.1
Ensembl_TRS: ENSMUST00000005826
Protein sequencees
Ensembl_PRO: ENSMUSP00000005826
RefSeq: XP_030100721.1, NP_080720.1
Others
UniRef100: UniRef100_Q9CZU6
UniRef90: UniRef90_O75390
UniRef50: UniRef50_O75390
UniGene: Mm.58836
CCDS: CCDS24273.1

全选

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