| Type | Description |
|---|---|
| Definition | crystallin, mu |
| Date | Results | Publications |
|---|---|---|
| 2019-09-21 12:33:00 | results suggest that CRYM deficiency leads to obesity and lipogenesis, possibly in part through increasing the food intake of mice fed a high-fat diet. | 30545633 |
| 2017-08-19 11:15:00 | The results demonstrated that Crym is a crucial regulator of muscle plasticity, controlling metabolic and contractile properties of myofibers, and thus the selective inactivation of Crym may be a potential therapeutic target for muscle-wasting diseases. | 26718889 |
| 2015-11-28 10:56:00 | Reduction of Crym expression in Huntington's disease (HD) could render striatal neurons more susceptible to mutant huntingtin suggesting that Crym may be a key determinant of the vulnerability of the striatum. | 25398949 |
| 2015-04-18 13:03:00 | CRYM expression increases and sustains the T3 responsiveness of genes in cells, especially with alteration of the pericellular T3 concentration. | 24646676 |
| 2014-05-17 15:26:00 | Comparison of the apo and NADPH forms reveals a rearrangement of the protein upon NADPH binding that reduces the degrees of freedom of several residues and traps the conformation of the binding pocket in a more T3 competent state. | 24467707 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
CRYM_MOUSE,
Q3UPX0_MOUSE
UniprotKB:
O54983,
Q3UPX0
UniParc:
UPI000000B754
EMBL:
AK143116,
AF039391,
AK163781,
BC045159,
AK138422
Ensembl:
ENSMUSG00000030905
KO:
mmu:12971
|
| Nucleutide sequences |
EMBL-CDS:
AAB94770.1,
AAH45159.1,
BAE23654.1,
BAE25274.1,
BAE37489.1
Ensembl_TRS:
ENSMUST00000033198
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000033198
RefSeq:
NP_057878.1
|
| Others |
UniRef100:
UniRef100_O54983
UniRef90:
UniRef90_O54983
UniRef50:
UniRef50_Q14894
UniGene:
Mm.9114
CCDS:
CCDS21794.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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