| Type | Description |
|---|---|
| Definition | crystallin, gamma S |
| Date | Results | Publications |
|---|---|---|
| 2012-10-13 11:08:00 | gammaS may have a functional role related to actin, perhaps in 'shepherding' filaments to maintain the optical properties of the lens cytoplasm and normal fiber cell maturation | 22715935 |
| 2010-08-30 11:08:00 | Mutant Crygs gene can lead to changes of BFSP/filensin and other crystallins. Changes to these crystallins, together, may secondarily lead to cataract formation. | 20596256 |
| 2010-01-21 00:00:00 | disruption of the Hsf4 gene leads to cataracts via at least three pathways: down-regulation of gamma-crystallin, particularly gamma S-crystallin; decreased lens beaded filament expression; and loss of post-translational modification of alpha A-crystallin | 19224648 |
| 2010-01-21 00:00:00 | gammaS consists of two topologically similar domains, arranged with an approximate twofold symmetry, and each domain shows close structural homology to closely related domains found in other members of the gamma-crystallin family. | 16260758 |
| 2010-01-21 00:00:00 | mutation causes autosomal recessive cataracts; likely to be involved in epithelial cell proliferation, apoptosis, and migration | 12079281 |
| Type | IDs |
|---|---|
| Synonymous | AI327013, Opj, rncat |
| Gene |
UniProtKB-ID:
CRYGS_MOUSE,
Q3UPY3_MOUSE
UniprotKB:
O35486,
Q3UPY3
UniParc:
UPI00000297D8
EMBL:
AF055702,
BC056452,
AF055703,
AF032995,
AK143060
Ensembl:
ENSMUSG00000033501
KO:
mmu:12970
|
| Nucleutide sequences |
EMBL-CDS:
AAH56452.1,
AAC53579.1,
AAC40120.1,
BAE25261.1
Ensembl_TRS:
ENSMUST00000040592
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000043588
RefSeq:
NP_034097.1,
XP_006521818.1
|
| Others |
UniRef100:
UniRef100_O35486
UniRef90:
UniRef90_O35486
UniRef50:
UniRef50_P22914
UniGene:
Mm.6253
CCDS:
CCDS28069.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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