| Type | Description |
|---|---|
| Definition | DIS3 like 3'-5' exoribonuclease 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-12 16:05:00 | DIS3L2 and LSm proteins are involved in the surveillance of Sm ring-deficient snRNAs. | 32374871 |
| 2020-08-29 12:48:00 | AGO-bound mature miRNAs are oligouridylated by TUTs and subsequently degraded by DIS3L2. | 32488030 |
| 2020-08-22 15:28:00 | The Perlman syndrome DIS3L2 exoribonuclease safeguards endoplasmic reticulum-targeted mRNA translation and calcium ion homeostasis. | 32457326 |
| 2020-06-06 10:26:00 | Findings indicate a role for DIS3 like 3'-5' exoribonuclease 2 (DIS3L2) and uridylation in nonsense-mediated mRNA decay (NMD). | 31466720 |
| 2020-05-30 12:17:00 | our findings uncover an oncogenic role of DIS3L2, in which it promotes liver cancer progression through a previously unappreciated mechanism of regulating hnRNP U-mediated alterative splicing | 31331910 |
| Type | IDs |
|---|---|
| Synonymous | FAM6A, PRLMNS, hDIS3L2 |
| Gene |
UniProtKB-ID:
DI3L2_HUMAN
UniprotKB:
Q8IYB7
UniParc:
UPI000006FBF7,
UPI000004BF03,
UPI000049DF3D,
UPI000162779F,
UPI00002097D6
EMBL:
AF443854,
AC068134,
AC093374,
AC138658,
AK094293,
AL834174,
BC026166,
AC019130,
BC036113,
BX648325
Ensembl:
ENSG00000144535
KO:
hsa:129563
|
| Nucleutide sequences |
EMBL-CDS:
AAX82031.1,
AAH36113.2,
CAH10694.1,
BAC04324.1,
AAH26166.1,
AAP97321.1,
AAY24086.1,
CAH10545.1
Ensembl_TRS:
ENST00000445090,
ENST00000409307,
ENST00000325385,
ENST00000433430,
ENST00000273009,
ENST00000409401,
ENST00000390005
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000386799,
ENSP00000391175,
ENSP00000386594,
ENSP00000388999,
ENSP00000374655,
ENSP00000315569,
ENSP00000273009
RefSeq:
NP_001244210.1,
NP_001244211.1,
NP_689596.4
|
| Others |
UniRef100:
UniRef100_Q8IYB7
UniRef90:
UniRef90_Q8IYB7
UniRef50:
UniRef50_Q8IYB7
UniGene:
Hs.732236
CCDS:
CCDS58752.1,
CCDS42834.1,
CCDS58753.1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| 1 |
National Cancer Institute |
4 |
| 2 |
University of Toronto |
3 |
| 3 |
Max Planck Institute of Molecular Cell Biology and Genetics |
2 |
| 4 |
CEITEC-Central European Institute of Technology |
2 |
| 5 |
Lunenfeld-Tanenbaum Research Institute |
2 |
| 排名 | 研究人员 | 文献 |
|---|---|---|
| 1 |
Kari Stefansson |
2 |
| 2 |
Unnur Thorsteinsdottir |
2 |
| 3 |
Gudmar Thorleifsson |
2 |
| 4 |
Lambertus A Kiemeney |
2 |
| 5 |
Valgerdur Steinthorsdottir |
2 |