例如:"NBL1", "4681", "drought"
收藏
129563 DIS3L2

129563

DIS3L2

DIS3 like 3'-5' exoribonuclease 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition DIS3 like 3'-5' exoribonuclease 2

研究结论

Date Results Publications
2020-09-12 16:05:00 DIS3L2 and LSm proteins are involved in the surveillance of Sm ring-deficient snRNAs. 32374871
2020-08-29 12:48:00 AGO-bound mature miRNAs are oligouridylated by TUTs and subsequently degraded by DIS3L2. 32488030
2020-08-22 15:28:00 The Perlman syndrome DIS3L2 exoribonuclease safeguards endoplasmic reticulum-targeted mRNA translation and calcium ion homeostasis. 32457326
2020-06-06 10:26:00 Findings indicate a role for DIS3 like 3'-5' exoribonuclease 2 (DIS3L2) and uridylation in nonsense-mediated mRNA decay (NMD). 31466720
2020-05-30 12:17:00 our findings uncover an oncogenic role of DIS3L2, in which it promotes liver cancer progression through a previously unappreciated mechanism of regulating hnRNP U-mediated alterative splicing 31331910

名称对应

Type IDs
Synonymous FAM6A, PRLMNS, hDIS3L2
Gene
UniProtKB-ID: DI3L2_HUMAN
UniprotKB: Q8IYB7
UniParc: UPI000006FBF7, UPI000004BF03, UPI000049DF3D, UPI000162779F, UPI00002097D6
EMBL: AF443854, AC068134, AC093374, AC138658, AK094293, AL834174, BC026166, AC019130, BC036113, BX648325
Ensembl: ENSG00000144535
KO: hsa:129563
Nucleutide sequences
EMBL-CDS: AAX82031.1, AAH36113.2, CAH10694.1, BAC04324.1, AAH26166.1, AAP97321.1, AAY24086.1, CAH10545.1
Ensembl_TRS: ENST00000445090, ENST00000409307, ENST00000325385, ENST00000433430, ENST00000273009, ENST00000409401, ENST00000390005
Protein sequencees
Ensembl_PRO: ENSP00000386799, ENSP00000391175, ENSP00000386594, ENSP00000388999, ENSP00000374655, ENSP00000315569, ENSP00000273009
RefSeq: NP_001244210.1, NP_001244211.1, NP_689596.4
Others
UniRef100: UniRef100_Q8IYB7
UniRef90: UniRef90_Q8IYB7
UniRef50: UniRef50_Q8IYB7
UniGene: Hs.732236
CCDS: CCDS58752.1, CCDS42834.1, CCDS58753.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员