| Type | Description |
|---|---|
| Definition | crystallin, alpha B |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:22:00 | The transcription factor CREB acts as an important regulator mediating oxidative stress-induced apoptosis by suppressing alphaB-crystallin expression. | 32554860 |
| 2020-06-13 12:06:00 | CRYAB promoted the proliferation and extracellular matrix production of chondrocytes, and inhibited chondrocytes apoptosis and cartilage degradation simultaneously. | 31226261 |
| 2020-05-02 11:33:00 | CRYAB regulates inflammatory response in intestinal mucosa by inhibiting IKKbeta-mediated signaling. | 31481750 |
| 2020-03-07 11:31:00 | IF and TFEB activation are clinically relevant therapeutic strategies to rescue advanced R120G alphaB-crystallin mutant-induced cardiomyopathy by normalizing desmin localization via autophagy-dependent and autophagy-independent mechanisms. | 30773991 |
| 2019-06-15 10:17:00 | results reveal a novel function for extracellular CRYAB in the regulation of neuroinflammation; targeting extracellular CRYAB-modulated neuroinflammation is a potential therapeutic intervention for multiple sclerosis | 30497777 |
| Type | IDs |
|---|---|
| Synonymous | Crya-2, Crya2, HspB5, P23 |
| Gene |
UniProtKB-ID:
CRYAB_MOUSE,
Q52L78_MOUSE
UniprotKB:
P23927,
Q52L78
UniParc:
UPI00000018EE
EMBL:
BC010768,
BC094033,
AK168999,
AK146556,
M73741,
M25770,
M63170,
CT010341
Ensembl:
ENSMUSG00000032060
KO:
mmu:12955
|
| Nucleutide sequences |
EMBL-CDS:
AAH10768.1,
AAA37133.1,
AAA37472.1,
AAA67045.1,
BAE27257.1,
CAJ18549.1,
AAH94033.1,
BAE40798.1
Ensembl_TRS:
ENSMUST00000217475,
ENSMUST00000216755,
ENSMUST00000034562,
ENSMUST00000214962
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000150669,
ENSMUSP00000149803,
ENSMUSP00000149759,
ENSMUSP00000034562
RefSeq:
XP_036010485.1,
NP_001276711.1,
NP_034094.1,
NP_001276713.1,
NP_001276714.1,
XP_030099896.1
|
| Others |
UniRef100:
UniRef100_P23927
UniRef90:
UniRef90_P23928
UniRef50:
UniRef50_P23928
UniGene:
Mm.178
CCDS:
CCDS23172.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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