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12950 Hapln1

12950

Hapln1

hyaluronan and proteoglycan link protein 1

protein-coding

Mus musculus

基因描述

Type Description
Definition hyaluronan and proteoglycan link protein 1

研究结论

Date Results Publications
2020-06-06 13:35:00 Findings establish promoter regions within the hyaluronan and proteoglycan link protein 1 (link protein) gene that are important for in vivo expression and identify the potential role of homeodomain-containing proteins in controlling cartilage and limb gene expression. 31470976
2020-03-07 12:08:00 A novel role of HAPLN1 loss was reported in the aging lymphatic ECM in mediating lymphatic endothelial permeability, thus permitting melanoma cells to escape from the lymphatic system to distant metastatic sites. 30279172
2014-10-25 10:57:00 Aggrecan, link protein and TN-R were identified to be essential for the neuroprotective properties of the perineuronal net. 24625978
2013-08-31 12:09:00 Mef2c regulates transcription of the extracellular matrix protein cartilage link protein 1 in the developing murine heart. 23468913
2010-10-23 10:04:00 our findings demonstrate that the formation of perineuronal nets triggered by neuronal Crtl1 synthesis is a key event in the diminuation of plasticity in the adult CNS 20566484

名称对应

Type IDs
Synonymous BB099155, CLP, Crtl1, Crtl1l, LP, LP-1
Gene
UniProtKB-ID: HPLN1_MOUSE
UniprotKB: Q9QUP5
UniParc: UPI0000003FCC
EMBL: BC066853, AF137275, AF098460, AF137277, AF139572, AK032750, AF137278, AF137276, AK048107
Ensembl: ENSMUSG00000021613
KO: mmu:12950
Nucleutide sequences
EMBL-CDS: BAC28007.1, AAF24977.1, BAC33244.1, AAD12253.1, AAH66853.1, AAF24166.1
Ensembl_TRS: ENSMUST00000022108
Protein sequencees
Ensembl_PRO: ENSMUSP00000022108
RefSeq: NP_038528.3, XP_006517138.1
Others
UniRef100: UniRef100_Q9QUP5
UniRef90: UniRef90_Q9QUP5
UniRef50: UniRef50_P03994
UniGene: Mm.266790
CCDS: CCDS26671.1

全选

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