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12946 Cr1l

12946

Cr1l

complement component (3b/4b) receptor 1-like

protein-coding

Mus musculus

基因描述

Type Description
Definition complement component (3b/4b) receptor 1-like

研究结论

Date Results Publications
2019-08-17 10:17:00 Our study uncovers a damaging effect of complement C3 or downstream complement activation in glaucoma, and it establishes AAV2.CR2-Crry as a viable therapeutic strategy to target pathogenic C3-mediated complement activation in the glaucomatous retina 30217731
2018-05-26 11:06:00 CRRY role in the retinal epithelium and photoreceptor degeneration 28348233
2017-10-07 12:43:00 Factor H and Crry are critical for regulating complement activation at distinct anatomic sites within the kidney. 27165610
2015-07-04 15:10:00 this study has provided direct evidence for a role of Crry in controlling spontaneous alternative pathway complement activation on renal tubular epithelial cells. 24850152
2011-11-05 10:09:00 HBx can up-regulate CD59 and Crry expression in podocytes through activating the P38 pathway. 21215189

名称对应

Type IDs
Synonymous Crry, Mcp, mCRY
Gene
UniProtKB-ID: CR1L_MOUSE
UniprotKB: Q64735
UniParc: UPI000002A0DE, UPI0000028807
EMBL: M23529, M34165, AK004825, M34169, M23446, BC028945, AC139206, M34164, M34171, M34173, M34166, M34168, AK160440, M34167, BC092048, M34172, M34170
Ensembl: ENSMUSG00000016481
KO: mmu:12946
Nucleutide sequences
EMBL-CDS: BAC25098.1, AAH92048.1, AAA37467.1, AAA37468.1, AAA37477.1, AAA37478.1, BAE35790.1, AAH28945.1
Ensembl_TRS: ENSMUST00000075451
Protein sequencees
Ensembl_PRO: ENSMUSP00000074902
RefSeq: NP_001341990.1, NP_001341989.1, NP_038527.2
Others
UniRef100: UniRef100_Q64735
UniRef90: UniRef90_Q64735
UniRef50: UniRef50_Q64735
UniGene: Mm.301652
CCDS: CCDS15641.1

全选

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研究热度

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