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12944 Crp

12944

Crp

C-reactive protein, pentraxin-related

protein-coding

Mus musculus

基因描述

Type Description
Definition C-reactive protein, pentraxin-related

研究结论

Date Results Publications
2019-04-13 11:30:00 this study shows that C-reactive protein impairs dendritic cell development, maturation, and function 29556231
2018-04-07 10:15:00 CRP is pathogenic in type-2 diabetes (T2DN). CRP may promote CD32b- NF-kappaB signaling to mediate renal inflammation; whereas, CRP may enhance renal fibrosis in T2DN via CD32b-Smad3-mTOR signaling. 27221338
2018-03-03 11:26:00 FcgammaRIIb and FcgammaRIII are involved in the CRP-induced expression of MMPs and TIMP-1 and the CRP-induced phosphorylation of p38, whereas the FcgammaR-independent pathway may regulate the CRP-induced MMP-11 expression and the CRP-induced ERK1/2 phosphorylation. 28539825
2017-10-21 11:14:00 C-reactive protein may promote acute kidney injury by impairing tubular epithelial cell regeneration via the CD32-Smad3-p27-driven inhibition of the CDK2/cyclin E complex. 27470679
2017-04-22 11:31:00 These results suggested that CRP/oxidized low density lipoprotein/beta 2-Glycoprotein I complexes may induce lipid accumulation and inflammation in macrophages via the p38/MAPK and NFkappaB signaling pathways. 27512978

名称对应

Type IDs
Synonymous AI255847
Gene
UniProtKB-ID: CRP_MOUSE
UniprotKB: P14847
UniParc: UPI0000024733
EMBL: X13588, AC131177, X17496
Ensembl: ENSMUSG00000037942
KO: mmu:12944
Nucleutide sequences
EMBL-CDS: CAA35531.1, CAA31928.1
Ensembl_TRS: ENSMUST00000038495
Protein sequencees
Ensembl_PRO: ENSMUSP00000044665
RefSeq: NP_031794.3
Others
UniRef100: UniRef100_P14847
UniRef90: UniRef90_P14847
UniRef50: UniRef50_P02741
UniGene: Mm.28767
CCDS: CCDS35787.1

全选

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研究热度

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