| Type | Description |
|---|---|
| Definition | v-crk avian sarcoma virus CT10 oncogene homolog |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:15:00 | Essential role of the Crk family-dosage in DiGeorge-like anomaly and metabolic homeostasis. | 32041892 |
| 2021-02-27 13:54:00 | Requirement for Crk and CrkL during postnatal lens development. | 32736680 |
| 2020-10-24 14:00:00 | Signaling adaptor protein Crk is involved in malignant feature of pancreatic cancer associated with phosphorylation of c-Met. | 32005519 |
| 2020-06-27 12:27:00 | these results indicate that CrkII negatively regulates osteoblast differentiation and function through JNK phosphorylation. Given that CrkII acts as a negative and positive regulator of osteoblast and osteoclast differentiation, respectively, the regulation of CrkII expression in bone cells may help to develop new strategies to enhance bone formation and inhibit bone resorption. | 31554784 |
| 2019-08-10 12:24:00 | Here, we show that the Crk family of adaptor proteins, Crk and Crkl, are required for mouse lens morphogenesis but not differentiation upon Fibroblast Growth Factor stimulation. | 29360039 |
| Type | IDs |
|---|---|
| Synonymous | Crk-I, Crk-II, Crk-III, Crk3, CrkIII, Crko, c-Crk, p38 |
| Gene |
UniProtKB-ID:
CRK_MOUSE,
Q5ND50_MOUSE,
Q8JZR2_MOUSE,
Q3TQV3_MOUSE,
Q5ND51_MOUSE
UniprotKB:
Q64010,
Q5ND50,
Q8JZR2,
Q3TQV3,
Q5ND51
UniParc:
UPI0000003F6F,
UPI000002A724,
UPI00000E8853,
UPI00005B1D31,
UPI00005B1F52
EMBL:
AK139089,
S72408,
AY902336,
AK028179,
AK154987,
AK088519,
BC031149,
AL591440,
AK161356,
AK161761,
AK036905,
AK052795,
AK163291,
AK028488
Ensembl:
ENSMUSG00000017776
KO:
mmu:12928
|
| Nucleutide sequences |
EMBL-CDS:
AAB30755.1,
BAC25976.1,
BAE36345.1,
BAE23885.1,
BAC25792.1,
BAC40399.1,
AAH31149.1,
BAC29633.1,
BAC35149.1,
BAE37279.1,
AAX90621.1,
BAE32976.1,
BAE36562.1
Ensembl_TRS:
ENSMUST00000017920,
ENSMUST00000093115,
ENSMUST00000108425,
ENSMUST00000108426
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000017920,
ENSMUSP00000090803,
ENSMUSP00000104063,
ENSMUSP00000104064
RefSeq:
NP_598417.2,
NP_001264148.1,
NP_001264150.1,
XP_006532188.1,
XP_006532187.1
|
| Others |
UniRef100:
UniRef100_Q64010,
UniRef100_Q3TQV3,
UniRef100_Q5ND50,
UniRef100_Q8JZR2
UniRef90:
UniRef90_A0A1A6I0W4,
UniRef90_Q64010,
UniRef90_Q5ND50,
UniRef90_Q8JZR2
UniRef50:
UniRef50_K7EUR8,
UniRef50_P46108,
UniRef50_A0A2I3MEC4,
UniRef50_A0A1A6I0W4
UniGene:
Mm.280125
CCDS:
CCDS25055.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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