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12916 Crem

12916

Crem

cAMP responsive element modulator

protein-coding

Mus musculus

基因描述

Type Description
Definition cAMP responsive element modulator

研究结论

Date Results Publications
2021-02-27 13:54:00 Induction of ICER is superseded by smICER, challenging the impact of ICER under chronic beta-adrenergic stimulation. 32602979
2021-02-27 13:53:00 Novel insights into biological roles of inducible cAMP early repressor ICER. 32534736
2019-03-09 12:36:00 CREM-/- mice were more susceptible to E. histolytica amebic colitis 30228239
2018-08-04 10:06:00 Studied role and importance of inducible cAMP early repressor (ICER) in glutaminolysis and the generation of Th17 cells. Demonstrated the IL-17 promoting ICER works through the direct control of glutaminase 1 (Gls1) by binding its promoter. 29463741
2018-01-20 11:15:00 Deficiency in ICER elevated binding of NF-kappaB to promoters of pro-inflammatory genes and their subsequent gene expression. Mice deficient in ICER were hypersensitive to LPS-induced endotoxic shock and showed propagated inflammation. 28009352

名称对应

Type IDs
Synonymous ICER, ICERI
Gene
UniProtKB-ID: CREM_MOUSE, F6QWT6_MOUSE, D3Z326_MOUSE, D3Z0R0_MOUSE, Q78Z98_MOUSE, Q9CQ87_MOUSE, D3YXV5_MOUSE, D3Z2U7_MOUSE, D3Z011_MOUSE, E9PV35_MOUSE, F6VJ22_MOUSE, D3Z6A5_MOUSE, D3Z7M6_MOUSE, Q9D599_MOUSE, E9PWV9_MOUSE, Q3TTH6_MOUSE
UniprotKB: P27699, F6QWT6, D3Z326, D3Z0R0, Q78Z98, Q9CQ87, D3YXV5, D3Z2U7, D3Z011, E9PV35, F6VJ22, D3Z6A5, D3Z7M6, Q9D599, E9PWV9, Q3TTH6
UniParc: UPI0001889BCE, UPI0001B30113, UPI00001EBC73, UPI00015FF97E, UPI00005B1D35, UPI0001889BC5, UPI0001B30111, UPI00000222B3, UPI00015FF97A, UPI0001889BC2, UPI00015FF97D, UPI00015FF977, UPI00027CD72A, UPI00015FF978, UPI00000E6712, UPI00015FF979, UPI0001B30112, UPI0001889BC4, UPI00000E7858, UPI0001889BD0, UPI00000E61EA, UPI0001889BC8, UPI0001551E0E, UPI00015FF97C, UPI0001889BDF, UPI0001889BE0
EMBL: AK015641, AY738716, AK010806, AK161366, AY738719, AJ311667, M60285, AY738715, AK009841, AY738721, AY738718, AY738717, AJ292222, BC034856, AC117589
Ensembl: ENSMUSG00000063889
KO: mmu:12916
Nucleutide sequences
EMBL-CDS: CAC34846.1, AAV28556.1, AAA17496.1, AAV28551.1, AAA17497.1, AAV28553.1, AAV28555.1, AAV28554.1, AAV28552.1, AAA17495.1, CAC27134.1, BAB27192.1, AAH34856.1, BAB26536.1, BAB29910.1, BAE36349.1
Ensembl_TRS: ENSMUST00000154470, ENSMUST00000082141, ENSMUST00000154135, ENSMUST00000150235, ENSMUST00000165086, ENSMUST00000025069, ENSMUST00000154705, ENSMUST00000124747, ENSMUST00000136961, ENSMUST00000149803, ENSMUST00000151311, ENSMUST00000156234, ENSMUST00000144496, ENSMUST00000122958, ENSMUST00000151084, ENSMUST00000049942, ENSMUST00000154715, ENSMUST00000126578, ENSMUST00000142690
Protein sequencees
Ensembl_PRO: ENSMUSP00000118128, ENSMUSP00000080780, ENSMUSP00000122051, ENSMUSP00000025069, ENSMUSP00000121233, ENSMUSP00000127353, ENSMUSP00000119194, ENSMUSP00000121352, ENSMUSP00000115363, ENSMUSP00000121210, ENSMUSP00000118267, ENSMUSP00000121388, ENSMUSP00000120349, ENSMUSP00000121118, ENSMUSP00000118578, ENSMUSP00000061925, ENSMUSP00000122179, ENSMUSP00000114780, ENSMUSP00000122282
RefSeq: NP_001104323.1, XP_030106175.1, XP_030106160.1, NP_001104325.2, NP_001104322.1, XP_036016853.1, XP_006525643.1, XP_006525625.1, NP_001258435.1, XP_006525624.1, XP_006525622.1, XP_036016860.1, XP_006525639.1, XP_006525629.1, XP_036016856.1, XP_030106162.1, NP_001104321.1, XP_006525642.1, NP_038526.2, NP_001104328.1, XP_006525638.1, NP_001104327.1, XP_036016858.1, NP_001104329.1, NP_001104324.2, XP_030106161.1, NP_001258432.1, XP_006525617.1, XP_006525628.1, NP_001104320.1, NP_001104326.1, XP_006525623.1, XP_006525619.1, NP_001297995.1, NP_001297996.1, XP_036016859.1, XP_036016862.1, XP_006525633.1, XP_036016852.1, XP_030106165.1, XP_030106163.1, XP_036016861.1, XP_030106170.1, XP_006525618.1, XP_030106169.1, XP_006525636.1, XP_011245122.1, XP_030106166.1, XP_006525637.1, XP_006525631.1, NP_001258434.1, XP_030106171.1, XP_030106168.1, NP_001258433.1, XP_006525630.1, XP_006525620.1, XP_006525626.1, XP_006525627.1, XP_036016855.1, NP_001361762.1, XP_036016857.1, XP_030106173.1, XP_017173297.1
Others
UniRef100: UniRef100_F6VJ22, UniRef100_Q3TTH6, UniRef100_E9PV35, UniRef100_F6QWT6, UniRef100_D3Z2U7, UniRef100_D3Z326, UniRef100_D3Z7M6, UniRef100_D3Z6A5, UniRef100_D3YXV5, UniRef100_Q9D599, UniRef100_D3Z0R0, UniRef100_E9PWV9, UniRef100_D3Z011, UniRef100_Q9CQ87, UniRef100_P27699
UniRef90: UniRef90_Q3TTH6, UniRef90_Q03061-5, UniRef90_P27699-6, UniRef90_P79145, UniRef90_D3Z6A5, UniRef90_F6QWT6, UniRef90_P27699, UniRef90_Q9CQ87, UniRef90_D3Z011, UniRef90_A0A2K5VKP9, UniRef90_F6VJ22
UniRef50: UniRef50_P16220, UniRef50_H2SBD4, UniRef50_Q03060-20, UniRef50_A0A337STE3, UniRef50_A0A3L8SZ16, UniRef50_F6QWT6, UniRef50_M3W552, UniRef50_P79145, UniRef50_A0A2K5VKP9, UniRef50_P27699
UniGene: Mm.5244
CCDS: CCDS70864.1, CCDS70863.1, CCDS29031.2, CCDS50215.1, CCDS70862.1, CCDS50214.1

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