| Type | Description |
|---|---|
| Definition | complement receptor 2 |
| Date | Results | Publications |
|---|---|---|
| 2019-08-17 10:17:00 | Our study uncovers a damaging effect of complement C3 or downstream complement activation in glaucoma, and it establishes AAV2.CR2-Crry as a viable therapeutic strategy to target pathogenic C3-mediated complement activation in the glaucomatous retina | 30217731 |
| 2016-06-28 10:30:00 | These results demonstrate that local expression of Cr2 in the central nervous system is part of the axotomy reaction and is suggested to modulate subsequent complement mediated effects. | 26502875 |
| 2015-01-17 11:53:00 | Immunization of Cr1KO mice with a T cell-dependent antigen resulted in the normal initial expansion of B cells with a germinal center phenotype however these cells were preferentially lost in the Cr1KO animal over time (days). | 24636730 |
| 2014-12-06 13:08:00 | This study demonistrated that receptors for complement C3 fragments (CR2/CR1) may represent a promising future approach for therapeutic immunomodulation after traumatic brain injury. | 24885042 |
| 2014-07-26 11:58:00 | Data suggest that the Cr2KO mouse thus provides a new model system for the analysis of Cr1 and Cr2 functions in the immune response of the mouse. | 24012440 |
| Type | IDs |
|---|---|
| Synonymous | C3DR, CD21, CD35, Cr-1, Cr-2, Cr1 |
| Gene |
UniProtKB-ID:
Q9DC83_MOUSE,
A0A1B0GS59_MOUSE
UniprotKB:
Q9DC83,
A0A1B0GS59
UniParc:
UPI0003D78BD0,
UPI00000E5FCB
EMBL:
BC109344,
AK003072,
AC139206
Ensembl:
ENSMUSG00000026616
|
| Nucleutide sequences |
EMBL-CDS:
AAI09345.1,
BAB22548.1
Ensembl_TRS:
ENSMUST00000082321,
ENSMUST00000210219
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000080938,
ENSMUSP00000147804
RefSeq:
XP_006497287.1,
XP_006497285.1,
XP_017169539.1,
NP_031784.1,
NP_001355694.1,
XP_006497288.1
|
| Others |
UniRef100:
UniRef100_A0A1B0GS59,
UniRef100_Q9DC83
UniRef90:
UniRef90_A0A1B0GS59,
UniRef90_P19070
UniRef50:
UniRef50_P19070,
UniRef50_E3UM64
UniGene:
Mm.235387
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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