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1290 COL5A2

1290

COL5A2

collagen type V alpha 2 chain

protein-coding

Homo sapiens

基因描述

Type Description
Definition collagen type V alpha 2 chain

研究结论

Date Results Publications
2021-02-27 13:52:00 COL5A2 as a potential clinical biomarker for gastric cancer and renal metastasis. 33607786
2020-01-11 10:44:00 COL5A1 is an unfavorable factor for tumorigenesis, clinicopathological outcomes, and prognosis, whereas COL5A2 is only a favorable factor for prognosis in tongue squamous cell carcinoma 30972812
2018-07-07 12:11:00 Mutations affecting COL5A1 or COL5A2 are responsible for spectrum of mucocutaneous, ocular and facial features in 62 classical Ehlers-Danlos syndrome patients. 28485813
2018-03-24 10:35:00 Bladder cancer patients in COL5A2 low expression group were associated with better invasiveness (P < .0001), tumor grade (P=.001), T staging (P < .0001), N staging (P = .002), and a trend of better M staging (P = .053) than those in COL5A2 high expression group. These results indicated that COL5A2 might promote the progression of Bladder Cancer cells. 29517678
2016-06-11 11:24:00 COL5A2(+/-) humans, although unlikely to present with frank classic Ehlers-Danlos syndrome, are likely to have fragile connective tissues with increased susceptibility to trauma and certain chronic pathologic conditions. 25987251

名称对应

Type IDs
Synonymous EDSC, EDSCL2
Gene
UniProtKB-ID: CO5A2_HUMAN
UniprotKB: P05997
UniParc: UPI00006C511C
EMBL: J03051, AY016287, AY016295, AY016294, AC064833, Y14690, M11718, AY016288, AY016291, M10956, M11135, AC133106, J04478, M58529, X04758, AY016293, AY016289, BC043613, AY016292, AY016290, AB209045
Ensembl: ENSG00000204262
KO: hsa:1290
Nucleutide sequences
EMBL-CDS: CAA75002.1, AAL13165.1, AAY24185.1, CAA28454.1, AAA51858.1, AAA52058.1, AAA51859.1, AAA51857.1, AAL13166.1, AAA52007.1, AAH43613.1, AAC41699.1, BAD92282.1
Ensembl_TRS: ENST00000374866
Protein sequencees
Ensembl_PRO: ENSP00000364000
RefSeq: XP_011508875.1, NP_000384.2
Others
UniRef100: UniRef100_P05997
UniRef90: UniRef90_P05997
UniRef50: UniRef50_P05997
UniGene: Hs.445827
CCDS: CCDS33350.1

全选

研究热度
发表文献
研究结论
热点单位
排名 科研单位 文献
1

University of Wisconsin

6
2

Howard Hughes Medical Institute

3
3

Koch Institute for Integrative Cancer Research

3
4

Vanderbilt University

3
5

Washington University School of Medicine

2
热点人员
排名 研究人员 文献
1

Scott M Williams

7
2

Ramkumar Menon

6
3

Daniel S Greenspan

4
4

Digna R Velez

4
5

Richard M Myers

3
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