| Type | Description |
|---|---|
| Definition | carnitine palmitoyltransferase 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-02 12:51:00 | Mitochondrial carnitine palmitoyltransferase 2 is involved in N(epsilon)-(carboxymethyl)-lysine-mediated diabetic nephropathy. | 31838081 |
| 2017-12-23 11:59:00 | Cpt2 is obligate enzyme in long-chain fatty acid (FA) oxidation; cardiac hypertrophy is linked to impaired FA oxidation. Data (including data from studies using transgenic/knockout mice) suggest that deficiency of Cpt2 in cardiac muscle leads to cardiac hypertrophy/dysfunction with eventual lethality without cardiac fibrosis; mTORC1 is activated in Cpt2(-/-) heart, but inhibition of mTORC1 does not prevent hypertrophy. | 28916721 |
| 2016-12-17 10:24:00 | Mice acclimatized to thermoneutrality revealed that Cpt2A-null interscapular brown adipose tissue failed to induce the expression of thermogenic genes such as Ucp1 and Pgc1a. | 26854223 |
| 2016-07-16 11:28:00 | Consistent with the known requirement for CPT2 in fatty acid oxidation, macrophages lacking CPT2 were unable to achieve b-oxidation of fatty acids yet still seemed to fully polarize toward an M2 state after stimulation with IL-4 in vitro and in vivo. | 26882249 |
| 2010-01-21 00:00:00 | Cpt2 transcripts decrease following fertilization to undetectable levels and are present again later at the morula stage | 15237209 |
| Type | IDs |
|---|---|
| Synonymous | AI323697, CPTII |
| Gene |
UniProtKB-ID:
CPT2_MOUSE,
Q3UN55_MOUSE
UniprotKB:
P52825,
Q3UN55
UniParc:
UPI00005AC2F2,
UPI0000022F36
EMBL:
AK144441,
BC145859,
U01166,
U01170,
BC138514,
AL611936,
U01163,
U01168,
U01167,
U01169,
AK169038,
CH466527
Ensembl:
ENSMUSG00000028607
KO:
mmu:12896
|
| Nucleutide sequences |
EMBL-CDS:
AAI45860.1,
BAE40828.1,
EDL30761.1,
AAI38515.1,
AAA18921.1,
AAA18922.1,
BAE25892.1
Ensembl_TRS:
ENSMUST00000030345
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000030345
RefSeq:
NP_034079.2
|
| Others |
UniRef100:
UniRef100_P52825,
UniRef100_Q3UN55
UniRef90:
UniRef90_P52825
UniRef50:
UniRef50_P18886
UniGene:
Mm.307620
CCDS:
CCDS18443.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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