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12895 Cpt1b

12895

Cpt1b

carnitine palmitoyltransferase 1b, muscle

protein-coding

Mus musculus

基因描述

Type Description
Definition carnitine palmitoyltransferase 1b, muscle

研究结论

Date Results Publications
2020-07-25 11:14:00 Our results reveal that uc.323 is a conserved T-UCR that inhibits cardiac hypertrophy, potentially by regulating the transcription of CPT1b via interaction with EZH2. 31735087
2019-08-17 10:04:00 Knock in mouse model expressing the CPT1BE3A mutant enzyme, which has reduced sensitivity to malonyl-CoA, demonstrates increased cardiac fatty acid oxidation. 29635338
2018-07-14 10:10:00 Cpt1b role in the mitochondrial fat oxidation in the lipid induced inffalmation in skeletal muscle. 27892502
2017-07-01 13:01:00 Cardiac CPT-1b suppression protects against the aggravation of cardiac morphology and function associated with HFD feeding. CPT-1b represents a potential therapeutic target for the treatment of cardiac dysfunction related to metabolic diseases such as obesity and diabetes. 27804274
2015-11-21 11:25:00 Data show that peroxisome-proliferator-activated receptor beta/delta (PPARbeta/delta) activation restored the lipid-induced endothelial dysfunction by up-regulation of carnitine palmitoyltransferase)-1 (CPT-1). 26253087

名称对应

Type IDs
Synonymous Cpt1, Cpt1-m, Cpti, Cpti-m, M-cpti
Gene
UniProtKB-ID: CPT1B_MOUSE
UniprotKB: Q924X2
UniParc: UPI00000E690C
EMBL: BC018270, AJ278284, AB010826, AF017174
Ensembl: ENSMUSG00000078937
KO: mmu:12895
Nucleutide sequences
EMBL-CDS: CAC40150.1, BAA88685.1, AAC31640.2, AAH18270.1
Ensembl_TRS: ENSMUST00000109313
Protein sequencees
Ensembl_PRO: ENSMUSP00000104936
RefSeq: NP_034078.2
Others
UniRef100: UniRef100_Q924X2
UniRef90: UniRef90_Q63704
UniRef50: UniRef50_P32198
UniGene: Mm.227738
CCDS: CCDS27749.1

全选

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研究热度

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