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12894 Cpt1a

12894

Cpt1a

carnitine palmitoyltransferase 1a, liver

protein-coding

Mus musculus

基因描述

Type Description
Definition carnitine palmitoyltransferase 1a, liver

研究结论

Date Results Publications
2020-10-31 13:14:00 CPT1A plays a key role in the development and treatment of multiple sclerosis and experimental autoimmune encephalomyelitis. 31527712
2020-05-16 11:54:00 findings indicate that downregulation of carnitine palmitoyltransferase 1a by lipid content modulates macrophage phagocytosis and inflammatory phenotype 31823799
2019-11-09 11:55:00 CPT gene upregulation increased mitochondrial reactive oxygen species and led to cell apoptosis. 29795111
2019-11-09 10:17:00 Diet-induced hepatic steatosis activates Ras to promote hepatocarcinogenesis via CPT1alpha pathway. 30401637
2019-10-26 11:03:00 these data further implicate CPT-I flux as a key event influencing metabolic interactions during exercise, as a decline in l-carnitine sensitivity in addition to availability at higher power outputs could impair mitochondrial fatty acid oxidation. 30635360

名称对应

Type IDs
Synonymous C730027G07, CPTI, Cpt1
Gene
UniProtKB-ID: CPT1A_MOUSE, Q7TQD5_MOUSE, Q3UGT1_MOUSE
UniprotKB: P97742, Q7TQD5, Q3UGT1
UniParc: UPI0000192DF3, UPI00005AC6D2
EMBL: AK133472, S82796, AK147770, AF017175, BC046383, AK136487, BC054791, AK149688, AK077454, BC038395, AK050213
Ensembl: ENSMUSG00000024900
KO: mmu:12894
Nucleutide sequences
EMBL-CDS: BAC34126.2, AAB39370.1, BAC36808.1, AAH46383.1, AAC31641.1, AAH38395.1, AAH54791.1, BAE21673.1, BAE29027.1, BAE23002.1, BAE28126.1
Ensembl_TRS: ENSMUST00000025835
Protein sequencees
Ensembl_PRO: ENSMUSP00000025835
RefSeq: NP_038523.2, XP_006531722.1, XP_006531717.1, XP_011246904.1, XP_006531721.1, XP_036017309.1, XP_036017310.1
Others
UniRef100: UniRef100_P97742, UniRef100_Q3UGT1
UniRef90: UniRef90_P32198
UniRef50: UniRef50_P32198
UniGene: Mm.18522
CCDS: CCDS29395.1

全选

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