| Type | Description |
|---|---|
| Definition | complexin 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-28 12:08:00 | data suggest that CPLX2 inhibits spontaneous secretion of IgM and IgG1 from splenic antibody-secreting cells (ASCs). This study provides new insight into the mechanism of antibody secretion of ASCs. | 31691534 |
| 2019-12-21 10:39:00 | the C2B domain of syt1, independent of complexin, is the molecular clamp that arrests synaptic vesicles prior to Ca(2+)-triggered fusion. | 31501440 |
| 2018-12-22 11:35:00 | We describe a high degree of structural similarity between the CpxII CTD and the SNAP25-SN1 domain (C-terminal half) and show that the CTD peptide lowers the rate of SDS-resistant SNARE complex formation in vitro. Moreover, corresponding CpxII:SNAP25 chimeras do restore complexin's function and even 'superclamp' tonic secretion. | 30044227 |
| 2015-07-25 11:16:00 | Complexin II is a central target molecule that links NADPH oxidase-derived reactive oxygen species to glutamate-mediated neuronal excitotoxicity in ischemic stroke. | 23982049 |
| 2014-05-24 10:54:00 | CpxII attenuates fluctuations of the early fusion pore and slows its expansion. | 24687280 |
| Type | IDs |
|---|---|
| Synonymous | 921-L, AI413745, AW492120, Gm34843 |
| Gene |
UniProtKB-ID:
CPLX2_MOUSE
UniprotKB:
P84086
UniParc:
UPI0000027525
EMBL:
U35101,
BN000501,
D38613,
BN000502
Ensembl:
ENSMUSG00000025867
KO:
mmu:12890
|
| Nucleutide sequences |
EMBL-CDS:
CAG26662.1,
BAA07604.1,
CAG26661.1,
AAC52272.1
Ensembl_TRS:
ENSMUST00000026985
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000026985
RefSeq:
NP_034076.1,
NP_001349147.1,
XP_017170865.1
|
| Others |
UniRef100:
UniRef100_Q6PUV4
UniRef90:
UniRef90_Q6PUV4
UniRef50:
UniRef50_Q6PUV4
UniGene:
Mm.268902
CCDS:
CCDS36667.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员