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12889 Cplx1

12889

Cplx1

complexin 1

protein-coding

Mus musculus

基因描述

Type Description
Definition complexin 1

研究结论

Date Results Publications
2019-12-21 10:39:00 the C2B domain of syt1, independent of complexin, is the molecular clamp that arrests synaptic vesicles prior to Ca(2+)-triggered fusion. 31501440
2016-05-21 10:12:00 The response of CPLX1 and Foxp1 levels to SNCA deficiency supports the notion that these factors are regulated by altered physiological function of alpha-synuclein. 25112678
2015-08-22 10:30:00 In the absence of Cplx1, synaptic vesicles remain unstable and prone to premature fusion. 26019341
2013-12-07 11:19:00 Cplx 1 and 2 play a role in facilitating vesicle priming, and also lead to the new hypothesis that Cplxs may synchronize vesicle release by promoting coupling between secretory vesicles and calcium channels. 23401610
2013-03-23 10:34:00 Complexin-1 carboxyl-terminal domain binds lipids through a novel protein motif by targeting complexin-1 to synaptic vesicles. 23352168

名称对应

Type IDs
Synonymous 921-S
Gene
UniProtKB-ID: CPLX1_MOUSE
UniprotKB: P63040
UniParc: UPI000002996A
EMBL: AK134820, D38614, BC014803, AK159026, AK158166
Ensembl: ENSMUSG00000033615
KO: mmu:12889
Nucleutide sequences
EMBL-CDS: BAE22299.1, BAA07605.1, BAE34774.1, AAH14803.1, BAE34390.1
Ensembl_TRS: ENSMUST00000046892
Protein sequencees
Ensembl_PRO: ENSMUSP00000038502
RefSeq: NP_031782.3
Others
UniRef100: UniRef100_P63040
UniRef90: UniRef90_P63040
UniRef50: UniRef50_O14810
UniGene: Mm.5195
CCDS: CCDS39206.1

全选

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研究热度

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