| Type | Description |
|---|---|
| Definition | charged multivesicular body protein 4B |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:27:00 | ESCRT-III controls nuclear envelope deformation induced by progerin. | 33139753 |
| 2020-07-11 10:10:00 | CHMP4B was localized to primary cilia in mammalian cells. Knockdown of CHMP4B interfered with cilium assembly and also caused fragmentation of preexisting cilia. | 31914703 |
| 2017-10-14 13:03:00 | Data (including data from studies using transgenic mice) suggest that the process leading to microparticle release from cardiac myocytes involves recruitment of CHMP4B protein to the forming microparticle membrane which also contains cBIN1; plasma cBIN1 is reduced in patients with heart failure as compared to control subjects. (CHMP4B = charged multivesicular body protein 4B; cBIN1 = cardiac bridging integrator 1) | 28806752 |
| 2016-07-30 11:05:00 | homologous domain of human Bro1 domain-containing proteins, Alix and Brox, binds CHMP4B but not STAM2, despite their high structural similarity | 26866605 |
| 2016-07-16 11:29:00 | The ESCRT-III subunit CHMP4B is a key effector in abscission, whereas its paralogue, CHMP4C, is a component in the abscission checkpoint that delays abscission until chromatin is cleared from the intercellular bridge. | 26929449 |
| Type | IDs |
|---|---|
| Synonymous | C20orf178, CHMP4A, CTPP3, CTRCT31, SNF7, SNF7-2, Shax1, VPS32B, Vps32-2, dJ553F4.4 |
| Gene |
UniProtKB-ID:
CHM4B_HUMAN
UniprotKB:
Q9H444
UniParc:
UPI0000128625
EMBL:
AL050349,
BC033859,
AB100261,
CH471077,
AY329085
Ensembl:
ENSG00000101421
KO:
hsa:128866
|
| Nucleutide sequences |
EMBL-CDS:
EAW76293.1,
AAQ91194.1,
BAC79375.1,
AAH33859.1,
EAW76294.1
Ensembl_TRS:
ENST00000217402
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000217402
RefSeq:
NP_789782.1
|
| Others |
UniRef100:
UniRef100_Q9H444
UniRef90:
UniRef90_Q9H444
UniRef50:
UniRef50_Q9H444
UniGene:
Hs.472471
CCDS:
CCDS13228.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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