| Type | Description |
|---|---|
| Definition | carboxypeptidase E |
| Date | Results | Publications |
|---|---|---|
| 2020-04-04 12:00:00 | It shows that although carboxypeptidase E (CPE) is not directly OGlcNAc modified in islets, overexpression of the suspected OGT target eIF4G1, previously shown to regulate CPE translation in beta-cells, increases islet CPE levels, and fully reverses betaOGTKO islet-induced hyperproinsulinemia. | 31300553 |
| 2019-08-24 11:07:00 | HT22 cells and embryonic cortical neurons overexpressing 40 kDa (CPE/NF-alpha1)-DeltaN exhibited enhanced proliferation, which was inhibited by IGFBP2 short interfering RNA treatment | 30063439 |
| 2018-03-10 12:14:00 | Cpe knockout leads to dysfunction of BDNF-TRKB signaling in hippocampus and lack of long-term potentiation formation. | 28386642 |
| 2017-12-25 01:02:00 | NF-alpha1 is critical for regulating antiproliferation and cell fate determination, through differentiating embryonic stem cells to GFAP-positive astrocytes for normal neurodevelopment. | 27709799 |
| 2016-10-08 11:41:00 | we show by RNA silencing that CPE and SgIII play a synergistic role in the trafficking of POMC to granules of the regulated secretory pathway in AtT20 cells | 26646096 |
| Type | IDs |
|---|---|
| Synonymous | CPH, Cph-1, Cph1, NF-alpha1, R74677, fat |
| Gene |
UniProtKB-ID:
CBPE_MOUSE,
Q543R4_MOUSE
UniprotKB:
Q00493,
Q543R4
UniParc:
UPI00000018D5
EMBL:
AK047891,
U23184,
BC010197,
X61232
Ensembl:
ENSMUSG00000037852
KO:
mmu:12876
|
| Nucleutide sequences |
EMBL-CDS:
AAH10197.1,
CAA43550.1,
AAB60488.1,
BAC33184.1
Ensembl_TRS:
ENSMUST00000048967
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000048555
RefSeq:
NP_038522.2
|
| Others |
UniRef100:
UniRef100_Q00493
UniRef90:
UniRef90_Q00493
UniRef50:
UniRef50_Q00493
UniGene:
Mm.31395,
Mm.470333
CCDS:
CCDS22327.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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