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128710 SLX4IP

128710

SLX4IP

SLX4 interacting protein

protein-coding

Homo sapiens

基因描述

Type Description
Definition SLX4 interacting protein

研究结论

Date Results Publications
2020-02-22 10:06:00 SLX4IP antagonizes promiscuous BLM Activity during alternative lengthening of telomeres maintenance in osteosarcoma cells. 31447390
2019-12-14 11:30:00 The binding of SLX4IP to both SLX4 and XPF-ERCC1 not only is vital for maintaining the stability of SLX4IP protein, but also promotes the interaction between SLX4 and XPF-ERCC1, especially after DNA damage. Collectively, these results demonstrate a new regulatory role for SLX4IP in maintaining an efficient SLX4-XPF-ERCC1 complex in interstrand crosslinks (ICLs) repair. 31495888
2014-11-08 13:09:00 The association of SLX4IP deletion with male sex suggest that differential illegitimate V(D)J-mediated recombination events contribute to the higher incidence rates of childhood acute lymphoblastic leukemia in boys compared with girls. 24045615
2011-09-14 12:13:00 C20orf94 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells. 21555518
2010-06-30 22:05:00 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) 20379614

名称对应

Type IDs
Synonymous C20orf94, bA204H22.1, bA254M13.1, dJ1099D15.3
Gene
UniProtKB-ID: SLX4I_HUMAN
UniprotKB: Q5VYV7
UniParc: UPI00001D8318
EMBL: AL035456, AL353599, BC026094, BC020787, AL133340
Ensembl: ENSG00000149346
KO: hsa:128710
Nucleutide sequences
EMBL-CDS: AAH20787.1, AAH26094.1
Ensembl_TRS: ENST00000334534
Protein sequencees
Ensembl_PRO: ENSP00000335557
RefSeq: XP_024307595.1, XP_016883140.1, XP_024307597.1, XP_016883136.1, XP_024307599.1, NP_001009608.1, XP_024307600.1, XP_024307598.1, XP_024307596.1
Others
UniRef100: UniRef100_Q5VYV7
UniRef90: UniRef90_Q5VYV7
UniRef50: UniRef50_Q5VYV7
UniGene: Hs.668782
CCDS: CCDS33439.1

全选

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