| Type | Description |
|---|---|
| Definition | COP9 signalosome subunit 2 |
| Date | Results | Publications |
|---|---|---|
| 2018-04-28 10:04:00 | Cops2, but not the whole COP9 signalosome, is essential for pluripotency maintenance in mouse embryonic stem cells. Down-regulation of Cops2 reduces expression of pluripotency genes, slows proliferation rate, arrests G2/M cell cycle, and compromises ESC embryoid differentiation. Cops2 binds to Nanog protein and prevents degradation. Cops2 functions as transcriptional corepressor to facilitate pluripotency maintenance. | 27226076 |
| 2012-01-28 11:25:00 | these data indicate that Alien/ESET complex is involved in TRbeta1-mediated transcription repression of E2F1 and provide a molecular basis of thyroid hormone-induced repression of proliferation. | 22079090 |
| 2010-01-21 00:00:00 | Expressed at an early stage of neuronal differentiation of P19 embryonal carcinoma cells. | 12524175 |
| 2010-01-21 00:00:00 | Nif3l1 participates in neural differentiation of P19 cells through cooperation with Trip15/CSN2. | 12522100 |
| 2010-01-21 00:00:00 | Disruption of Cops2 causes deficient cell proliferation, accumulation of p53 and cyclin E, and early embryonic death. | 12972599 |
| Type | IDs |
|---|---|
| Synonymous | AI315723, C85265, Csn2, Sgn2, TRIP-15, Trip15 |
| Gene |
UniProtKB-ID:
CSN2_MOUSE,
Q3V3N6_MOUSE
UniprotKB:
P61202,
Q3V3N6
UniParc:
UPI000006E920,
UPI000000167F
EMBL:
AF071312,
BC023096,
AF114246,
AF114247,
AK084421,
AF114238,
AF114240,
AF114239,
AK132207,
AF114237,
AF114241,
AF114245,
AF114236,
AK010383,
AF087688,
AK037757,
AF114244,
AF114242
Ensembl:
ENSMUSG00000027206
KO:
mmu:12848
|
| Nucleutide sequences |
EMBL-CDS:
AAD26162.1,
BAC39179.1,
BAB26900.1,
AAC36309.1,
AAH23096.1,
AAC33899.1,
BAE21033.1,
BAE20520.1
Ensembl_TRS:
ENSMUST00000110463,
ENSMUST00000028635
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000106090,
ENSMUSP00000028635
RefSeq:
NP_034069.2,
NP_001272442.1,
NP_001272441.1,
NP_001272436.1
|
| Others |
UniRef100:
UniRef100_Q3V3N6,
UniRef100_P61201
UniRef90:
UniRef90_Q3V3N6,
UniRef90_P61201
UniRef50:
UniRef50_P61201,
UniRef50_Q6IQT4
UniGene:
Mm.3596
CCDS:
CCDS16679.1,
CCDS71133.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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