| Type | Description |
|---|---|
| Definition | cartilage oligomeric matrix protein |
| Date | Results | Publications |
|---|---|---|
| 2020-04-04 12:44:00 | COMP regulation of BMPR2 appears to have an important role in controlling hypoxia-elicited changes in pulmonary artery superoxide and its potential regulation of contractile phenotype proteins. | 31389735 |
| 2019-12-07 10:43:00 | COMP-prohibitin 2 interaction in mitochondria plays an important role in maintaining the contractile phenotype of Vascular smooth muscle cells by regulating mitochondrial oxidative phosphorylation. | 29867124 |
| 2019-10-26 11:43:00 | While identifying the cellular pathologic mechanisms underlying the murine mutant (MT)-COMP model of pseudoachondroplasia, increased midline-1 (MID1) expression and mammalian target of rapamycin complex 1 (mTORC1) signaling was found. | 30553437 |
| 2019-09-14 12:50:00 | COMP N-terminus directly interacted with the EGF11-12 domain of Notch1 and activated Notch1 signaling, as evidenced by co-immunoprecipitation and mammalian two-hybrid assay. In conclusion, COMP served as a potential ligand of Notch1, thereby driving embryonic stem cell (ESC)-vascular smooth muscle cells (VSMCs) differentiation. | 29981303 |
| 2019-08-03 10:07:00 | presents the expression levels of ADAMTS-7 and COMP in the decidual tissues of mice and humans suffering from SA. | 30720083 |
| Type | IDs |
|---|---|
| Synonymous | TSP5 |
| Gene |
UniProtKB-ID:
COMP_MOUSE
UniprotKB:
Q9R0G6
UniParc:
UPI0000020D64
EMBL:
AF033530,
AC158553,
CH466569
Ensembl:
ENSMUSG00000031849
KO:
mmu:12845
|
| Nucleutide sequences |
EMBL-CDS:
EDL28815.1,
AAD01972.1
Ensembl_TRS:
ENSMUST00000003659
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000003659
RefSeq:
NP_057894.2,
XP_036009635.1,
XP_006509602.1
|
| Others |
UniRef100:
UniRef100_Q9R0G6
UniRef90:
UniRef90_Q9R0G6
UniRef50:
UniRef50_P49747
UniGene:
Mm.45071
CCDS:
CCDS22367.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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