| Type | Description |
|---|---|
| Definition | collagen, type VIII, alpha 1 |
| Date | Results | Publications |
|---|---|---|
| 2016-02-13 10:08:00 | Lack of collagen VIII reduces myofibroblast differentiation and fibrosis and promotes early mortality and left ventricle dilatation in response to pressure overload in mice. | 25694587 |
| 2014-03-08 10:53:00 | Type VIII collagen signals via beta1 integrin and RhoA to regulate MMP-2 expression and smooth muscle cell migration. | 23523587 |
| 2013-11-16 11:15:00 | Type VIII collagen mediates vessel wall remodeling after arterial injury and fibrous cap formation in atherosclerosis. | 23567639 |
| 2012-11-24 10:13:00 | in contrast to diabetic wild-type mice EMT-like changes were attenuated in diabetic Col8alpha1/alpha2-KO mice, indicating that collagen VIII may be 1 of the major inducers of epithelial-to-mesenchymal transition-like changes in kidneys of diabetic wild-type mice | 22759394 |
| 2011-05-28 11:00:00 | Type VIII collagen significantly modulates the effect of TGF-beta1 on mesangial cells and may therefore play a role in the pathogenesis of diabetic nephropathy. | 21372207 |
| Type | IDs |
|---|---|
| Synonymous | Col8a-1 |
| Gene |
UniProtKB-ID:
CO8A1_MOUSE
UniprotKB:
Q00780
UniParc:
UPI00000EB9E5
EMBL:
AK018742,
AK046370,
AK159542,
BC011061,
AK032048,
CT025753,
X66976,
X66977
Ensembl:
ENSMUSG00000068196
KO:
mmu:12837
|
| Nucleutide sequences |
EMBL-CDS:
BAE35169.1,
BAC32693.1,
AAH11061.1,
BAB31383.1,
BAC27670.1,
CAA47387.1
Ensembl_TRS:
ENSMUST00000089332
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000086745
RefSeq:
NP_031765.2
|
| Others |
UniRef100:
UniRef100_Q00780
UniRef90:
UniRef90_Q00780
UniRef50:
UniRef50_P27658
UniGene:
Mm.130388
CCDS:
CCDS37367.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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