| Type | Description |
|---|---|
| Definition | collagen, type VII, alpha 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-12-22 11:18:00 | Biophysical characterization of a pathogenic type VII collagen mutant is presented. The pathogenic mutant lowers thermal stability of the type VII collagen domain. Due to unfolding, protease cleavage sites in the domain become accessible. | 27989960 |
| 2018-07-21 11:30:00 | specifically binds and sequesters the innate immune activator cochlin in the lumen of lymphoid conduits | 29305555 |
| 2017-06-24 12:27:00 | miR-29 Regulates COL7A1 in Recessive Dystrophic Epidermolysis Bullosa, directly through targeting its 3' untranslated region at two distinct seed regions and indirectly through targeting an essential transcription factor required for basal COL7A1 expression, SP1 | 27328306 |
| 2015-08-01 11:47:00 | autoantibodies to COL7, independent of the targeted epitopes, induce blisters both ex vivo and in vivo | 25689103 |
| 2014-04-26 10:43:00 | The cystine knot is N-terminal to the collagen triple helix in in collagen type VII and IX and therefore probably impedes unfolding of the collagen triple helix from the N terminus. | 24385431 |
| Type | IDs |
|---|---|
| Synonymous | AW209154 |
| Gene |
UniProtKB-ID:
CO7A1_MOUSE
UniprotKB:
Q63870
UniParc:
UPI0000487A30
EMBL:
S63654,
U32107,
AC174646
Ensembl:
ENSMUSG00000025650
KO:
mmu:12836
|
| Nucleutide sequences |
EMBL-CDS:
AAB66593.1,
AAB27492.1
Ensembl_TRS:
ENSMUST00000112070,
ENSMUST00000026740
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000107701,
ENSMUSP00000026740
RefSeq:
NP_031764.2
|
| Others |
UniRef100:
UniRef100_Q63870
UniRef90:
UniRef90_Q63870
UniRef50:
UniRef50_Q02388
UniGene:
Mm.6200
CCDS:
CCDS40770.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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