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12830 Col4a5

12830

Col4a5

collagen, type IV, alpha 5

protein-coding

Mus musculus

基因描述

Type Description
Definition collagen, type IV, alpha 5

研究结论

Date Results Publications
2020-08-29 12:48:00 Development of an exon skipping therapy for X-linked Alport syndrome with truncating variants in COL4A5. 32488001
2018-06-09 10:41:00 although alpha5 and alpha6 (IV) chains are induced in the glomerular basement membrane in autosomal recessive Alport syndrome, their induction does not seem to play a major compensatory role 27377778
2017-03-25 12:31:00 Findings indicate a role for collagen alpha-5(IV) chain (Col4a5) in the regulation of macrophage responses to mycobacterial infection and identify Col4a5 as a potential target for the host-directed anti-mycobacterial therapy. 27432120
2016-04-30 10:44:00 alpha5(IV), but not alpha1(IV), promotes lung cancer cell proliferation and tumor angiogenesis through non-integrin collagen receptor DDR1-mediated ERK activation. 25992553
2015-02-14 12:48:00 Report novel mouse model of Alport syndrome with accumulation abnormal collagen alpha3alpha4alpha5(IV) trimers in the glomerular basement membrane. 24522496

名称对应

Type IDs
Gene
UniProtKB-ID: Q63ZW6_MOUSE
UniprotKB: Q63ZW6
UniParc: UPI00004408E8
EMBL: BX571779, BC082788, AL671856, AL713983, AK133179
Ensembl: ENSMUSG00000031274
KO: mmu:12830
Nucleutide sequences
EMBL-CDS: AAH82788.1, BAE21544.1
Ensembl_TRS: ENSMUST00000112931, ENSMUST00000112930
Protein sequencees
Ensembl_PRO: ENSMUSP00000108553, ENSMUSP00000108552
RefSeq: XP_006528760.1, NP_031762.2, NP_001156627.1, XP_017173861.1, XP_006528759.1
Others
UniRef100: UniRef100_Q63ZW6
UniRef90: UniRef90_P29400
UniRef50: UniRef50_P29400
UniGene: Mm.286892

全选

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研究热度

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