| Type | Description |
|---|---|
| Definition | collagen, type IV, alpha 4 |
| Date | Results | Publications |
|---|---|---|
| 2015-02-14 12:48:00 | Report novel mouse model of Alport syndrome with accumulation abnormal collagen alpha3alpha4alpha5(IV) trimers in the glomerular basement membrane. | 24522496 |
| 2011-02-26 10:58:00 | the NC1 domain of {alpha}3 chain is critical for {alpha}3{alpha}4{alpha}5 type IV collagen network assembly | 20847057 |
| 2010-01-21 00:00:00 | In kidney, when expressed onto Col4a3(-/-) background, human alpha3(IV) chain restored expression of and co-assembled with mouse alpha4 and alpha5(IV) chains at sites where human alpha3(IV) was expressed. All three chains required for network assembly. | 14507670 |
| 2010-01-21 00:00:00 | Alpha3(IV), alpha4(IV), and alpha5(IV) chains form a complex, which is a heterotrimer, and a defect in complex formation might be one of the molecular mechanisms underlying the pathogenesis of Alport syndrome. | 14633121 |
| 2010-01-21 00:00:00 | Collagen alpha3(IV) nor alpha4(IV) were detected in the lens capsule 2 weeks postnatal. | 12225806 |
| Type | IDs |
|---|---|
| Synonymous | E130010M05Rik, [a]4(IV) |
| Gene |
UniProtKB-ID:
CO4A4_MOUSE
UniprotKB:
Q9QZR9
UniParc:
UPI000002A09E,
UPI0000DA6CBD
EMBL:
BC117709,
AF169388,
Z35167
Ensembl:
ENSMUSG00000067158
KO:
mmu:12829
|
| Nucleutide sequences |
EMBL-CDS:
AAD50450.1,
AAI17710.1,
CAA84530.1
Ensembl_TRS:
ENSMUST00000087050
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000084282
RefSeq:
XP_011236954.1,
XP_011236955.1,
NP_031761.1
|
| Others |
UniRef100:
UniRef100_Q9QZR9
UniRef90:
UniRef90_Q9QZR9
UniRef50:
UniRef50_P53420
UniGene:
Mm.40253,
Mm.479772
CCDS:
CCDS35630.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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