| Type | Description |
|---|---|
| Definition | NAD(P)HX epimerase |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:14:00 | Cholesterol Efflux-Independent Modification of Lipid Rafts by AIBP (Apolipoprotein A-I Binding Protein). | 32787522 |
| 2020-11-28 13:12:00 | Novel NAXE variants as a cause for neurometabolic disorder: implications for treatment. | 31745726 |
| 2019-12-14 11:35:00 | Study finds that AIBP was expressed in inflammatory cells in the human lung. In vitro, AIBP in the presence of surfactant reduced LPS-induced p65, ERK1/2 and p38 phosphorylation, and IL-6 secretion by alveolar macrophages. These results suggest that lung injury increases pulmonary AIBP expression, which likely serves to promote cholesterol efflux to surfactant and reduce inflammation. | 30135304 |
| 2019-08-17 10:12:00 | These results suggest that AIBP inhibits inflammatory signaling pathways through binding to apoA-1 and stabilizing ABCA1, and subsequent alteration of lipid rafts and TLR4 in the cell membrane. | 29618705 |
| 2019-03-16 11:32:00 | These results provide circumstantial evidence that the epimerase has a metabolic function beyond NAD(P)HX repair and that this function involves vitamin B6. | 29654173 |
| Type | IDs |
|---|---|
| Synonymous | AIBP, APOA1BP, PEBEL, YJEFN1 |
| Gene |
UniProtKB-ID:
NNRE_HUMAN
UniprotKB:
Q8NCW5
UniParc:
UPI000013E275,
UPI00005764B0
EMBL:
AK294835,
AJ315849,
BC100934,
BC100931,
AL365181,
BC100932,
BC100933
Ensembl:
ENSG00000163382
KO:
hsa:128240
|
| Nucleutide sequences |
EMBL-CDS:
CAC86580.1,
AAI00935.1,
BAG57944.1,
AAI00932.1,
AAI00933.1,
AAI00934.1
Ensembl_TRS:
ENST00000368235
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000357218
RefSeq:
XP_016855808.1,
NP_658985.2
|
| Others |
UniRef100:
UniRef100_Q8NCW5
UniRef90:
UniRef90_Q8NCW5
UniRef50:
UniRef50_Q8NCW5
UniGene:
Hs.528320
CCDS:
CCDS1145.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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