| Type | Description |
|---|---|
| Definition | IQ motif containing GTPase activating protein 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-28 19:06:00 | IQGAP3 interacts with Rad17 to recruit the Mre11-Rad50-Nbs1 complex and contributes to radioresistance in lung cancer. | 32896617 |
| 2020-05-16 11:24:00 | IQGAP3 was upregulated in colorectal cancer at the tissue level and cellular level. Based on immunohistochemistry results of the tissue microarrays, authors demonstrated that higher expression of IQGAP3 was associated with higher tumor node metastasis stage (P = 0.005), higher incidence of lymph node metastasis (P = 0.004), and shorter overall survival (P = 0.022). | 31544570 |
| 2020-03-28 10:05:00 | Data found that the IQGAP3/BMP4 ratio in urinary cell-free DNA (ucfDNA) was significantly associated with recurrence-free survival (RFS) and progression-free survival (PFS) in non-muscle-invasive bladder cancer (NMIBC) patients suggesting that the IQGAP3/BMP4 ratio in ucfDNA may be an important independent factor for NMIBC prognosis. | 31088707 |
| 2020-02-22 11:39:00 | IQGAP3 may be a potential target gene for Kaempferol in the treatment of breast cancer. | 31605603 |
| 2019-03-09 12:31:00 | Both IQGAP3/BMP4 and IQGAP3/FAM107A ratios in ucfDNA were significantly higher in patients with BC than in those with hematuria. | 30446454 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
IQGA3_HUMAN
UniprotKB:
Q86VI3
UniParc:
UPI000046FFDD
EMBL:
AY253300,
AB105103,
AL365181,
AK122653
Ensembl:
ENSG00000183856
KO:
hsa:128239
|
| Nucleutide sequences |
EMBL-CDS:
BAC78211.1,
BAC85501.1,
AAP06954.1
Ensembl_TRS:
ENST00000361170
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000354451
RefSeq:
NP_839943.3,
XP_011507502.1,
XP_011507500.1,
XP_024309044.1,
XP_024309042.1,
XP_024309041.1,
XP_024309043.1,
XP_011507503.1
|
| Others |
UniRef100:
UniRef100_Q86VI3
UniRef90:
UniRef90_Q86VI3
UniRef50:
UniRef50_Q86VI3
UniGene:
Hs.591495
CCDS:
CCDS1144.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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