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12813 Col10a1

12813

Col10a1

collagen, type X, alpha 1

protein-coding

Mus musculus

基因描述

Type Description
Definition collagen, type X, alpha 1

研究结论

Date Results Publications
2019-11-16 11:51:00 The mechanistic link between COL10A1 and the TGF-beta1-SOX9 axis. 30154451
2019-05-11 11:02:00 treatment of the mice with carbamazepine (CBZ), a drug which stimulates intracellular proteolysis and alleviates ER stress, effectively reduced the disease severity in this model of metaphyseal chondrodysplasia type Schmid caused by a premature stop codon in the Col10a1 gene 30010889
2019-03-02 11:08:00 Metaphyseal chondrodysplasia Schmid type disease severity in mice is increased by ATF6alpha ablation and decreased by ATF6beta ablation triggered by mutations in collagen X. 29522813
2017-12-30 12:15:00 Results indicate that Cox-2 promotes Col10a1 expression and chondrocyte hypertrophy in vitro. 27121205
2017-01-28 11:20:00 In a model of instability-induced osteoarthritis, Col X was overexpressed in articular chondrocytes and osteophyte-forming cells in LOX-1(+)/(+) mice and was significantly downregulated in articular chondrocytes and osteophyte-forming cells in LOX-1(-)/(-) mice. 26901593

名称对应

Type IDs
Synonymous Col10, Col10a-1
Gene
UniProtKB-ID: COAA1_MOUSE
UniprotKB: Q05306
UniParc: UPI0000026913
EMBL: X65121, X63013, X67348, Z21610
Ensembl: ENSMUSG00000039462
KO: mmu:12813
Nucleutide sequences
EMBL-CDS: CAA79736.1, CAA47763.1, CAA44741.1, CAA46237.1
Ensembl_TRS: ENSMUST00000105511
Protein sequencees
Ensembl_PRO: ENSMUSP00000101150
RefSeq: NP_034055.1
Others
UniRef100: UniRef100_Q05306
UniRef90: UniRef90_Q05306
UniRef50: UniRef50_Q05306
UniGene: Mm.443177
CCDS: CCDS23780.1

全选

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研究热度

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