| Type | Description |
|---|---|
| Definition | cochlin |
| Date | Results | Publications |
|---|---|---|
| 2019-11-23 11:04:00 | Upon infection, the LCCL domain is cleaved from cochlin and secreted into the perilymph. This cleaved fragment sequesters infiltrating bacteria in the scala tympani and subsequently recruits resident immune cells to eliminate the bacteria. | 30905438 |
| 2015-07-25 10:06:00 | accumulation of acellular deposits in the incudomalleal and incudostapedial joints in Coch (G88E/G88E) mice similar to those found in human DFNA9-affected temporal bones | 25049087 |
| 2013-08-03 10:29:00 | study reports that cochlin is expressed by follicular dendritic cells (FDCs) and selectively localized in the fine extracellular network of conduits in the spleen and lymph nodes; by producing cochlin, FDCs contribute to the innate immune response in defense against bacteria | 23684986 |
| 2013-05-18 11:05:00 | COCH is a part of the downstream target network of BMP4 signaling and serves as another important effector to fine-tune mouse embryonic stem cell fates. | 23344953 |
| 2012-08-25 10:20:00 | Loss of Cochlin is associated with reduced intraocular pressure and mechanosensing. | 22496787 |
| Type | IDs |
|---|---|
| Synonymous | AW122937, Coch-5B2, D12H14S564E |
| Gene |
UniProtKB-ID:
COCH_MOUSE
UniprotKB:
Q62507
UniParc:
UPI0000003F7A
EMBL:
AK028690,
AK137336,
Z78163,
AF006741,
BC045137,
AK171875
Ensembl:
ENSMUSG00000020953
KO:
mmu:12810
|
| Nucleutide sequences |
EMBL-CDS:
CAB01565.1,
BAC26067.1,
BAE23310.1,
BAE42713.1,
AAC39949.1,
AAH45137.1
Ensembl_TRS:
ENSMUST00000085412,
ENSMUST00000164782
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000128127,
ENSMUSP00000082533
RefSeq:
NP_001185764.1,
NP_031754.1,
XP_017170432.1
|
| Others |
UniRef100:
UniRef100_Q62507
UniRef90:
UniRef90_Q62507
UniRef50:
UniRef50_O43405
UniGene:
Mm.21325
CCDS:
CCDS25901.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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