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12805 Cntn1

12805

Cntn1

contactin 1

protein-coding

Mus musculus

基因描述

Type Description
Definition contactin 1

研究结论

Date Results Publications
2020-04-18 11:33:00 Contactin-1 secreted by oligodendrocytes is a novel factor that influences nodal protein clustering in hippocampus. 31328333
2019-10-05 12:38:00 Study confirmed that the HNK-1 epitope was primarily expressed on TNC in the embryonic day 16 mouse brain and promoted neurite outgrowth. That this signal was mediated by CNTN, which is an HNK-1-expressing neuronal receptor. These results suggest that the HNK-1 epitope is a key modifier of TNC and CNTN in the regulation of embryonic brain development. 30629639
2016-10-22 10:59:00 Data indicate that Contactin-1 expression is dependent upon EBF factors; Cntn1 gene belongs to the expanding regulatory cascade driven by these transcriptional regulators so that changes in its activation may contribute to the Ebf2 null mutant phenotype 25820347
2016-03-19 11:35:00 It plays a role in hippocampal synaptic plasticity and memory also in aged mice, suggesting that it acts on molecular pathways related to apoptosis and amyloid-beta production. 25659859
2014-07-12 11:09:00 The F3/contactin plays a role in promoting adult hippocampal neurogenesis and that this effect correlates with improved synaptic function and memory. 23939883

名称对应

Type IDs
Synonymous AW495098, CNTN, F3cam, usl
Gene
UniProtKB-ID: CNTN1_MOUSE
UniprotKB: P12960
UniParc: UPI0000028AF2
EMBL: AK045710, BC066864, X14943, AK076273
Ensembl: ENSMUSG00000055022
KO: mmu:12805
Nucleutide sequences
EMBL-CDS: BAC36282.1, CAA33075.1, AAH66864.1, BAC32466.1
Ensembl_TRS: ENSMUST00000169825, ENSMUST00000000109, ENSMUST00000068378
Protein sequencees
Ensembl_PRO: ENSMUSP00000067842, ENSMUSP00000000109, ENSMUSP00000133063
RefSeq: XP_036015003.1, XP_006520446.1, NP_031753.1, NP_001153119.1, XP_036015004.1, NP_001153120.1, NP_001344980.1, XP_017171912.1, XP_017171911.1
Others
UniRef100: UniRef100_P12960
UniRef90: UniRef90_Q12860
UniRef50: UniRef50_Q12860
UniGene: Mm.4911, Mm.470343
CCDS: CCDS27763.1

全选

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