| Type | Description |
|---|---|
| Definition | calponin 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 10:11:00 | Cnn1(-/-) and Cnn2(-/-) double knockout aortic smooth muscle exhibits faster relaxation than that of wild type control. | 30707993 |
| 2019-09-14 12:36:00 | Cnn2 KO attenuated TGFb1-induced differentiation of myofibroblasts in culture as shown by the lower expression of SMA and less calcification than that of wild type (WT) cells. These findings present calponin 2 as a novel molecular target for the treatment and prevention of Calcific aortic valve | 30053524 |
| 2017-06-03 12:25:00 | Calponin 2-null macrophages and foam cells have significantly weakened cell adhesion, indicating a role of cytoskeleton regulation in macrophage functions and inflammatory responses, and a novel therapeutic target for the treatment of arterial atherosclerosis. | 27575021 |
| 2017-05-07 01:10:00 | The novel finding that calponin 2 regulates myosin-dependent CTF in non-muscle cells demonstrates a mechanism for controlling cell motility-based functions | 27733037 |
| 2014-03-22 11:42:00 | h2-Calponin gene expression is further affected by the treatment of cells with Notch inhibitor and activator, suggesting an upstream signaling mechanism. | 24285540 |
| Type | IDs |
|---|---|
| Synonymous | AA408047, AI324678, Calpo2 |
| Gene |
UniProtKB-ID:
CNN2_MOUSE,
Q543F3_MOUSE
UniprotKB:
Q08093,
Q543F3
UniParc:
UPI00000040C5
EMBL:
BC018482,
Z19543,
BC009144,
AK051845
Ensembl:
ENSMUSG00000004665
KO:
mmu:12798
|
| Nucleutide sequences |
EMBL-CDS:
AAH09144.1,
AAH18482.1,
CAA79603.1,
BAC34787.1
Ensembl_TRS:
ENSMUST00000004784
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000004784
RefSeq:
NP_031751.1
|
| Others |
UniRef100:
UniRef100_Q08093
UniRef90:
UniRef90_Q08093
UniRef50:
UniRef50_Q08093
UniGene:
Mm.157770
CCDS:
CCDS24003.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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