| Type | Description |
|---|---|
| Definition | synaptotagmin 2 |
| Date | Results | Publications |
|---|---|---|
| 2017-06-03 10:06:00 | the extended synaptotagmins (E-Syts), endoplasmic reticulum (ER) proteins that function as PtdIns(4,5)P2- and Ca(2+)-regulated tethers to the Pplasma membrane. | 27065097 |
| 2016-03-26 10:31:00 | SYT2 mutations cause a novel complex presynaptic congenital myasthenic syndrome characterized by motor neuropathy causing lower limb wasting and foot deformities, reflex potentiation following exercise and a prolonged period of posttetanic potentiation | 26519543 |
| 2014-11-08 10:52:00 | Synaptotagmin 2 mutations cause an autosomal-dominant form of lambert-eaton myasthenic syndrome and nonprogressive motor neuropathy. | 25192047 |
| 2013-01-26 11:07:00 | Human SytII is not an effective receptor for Botulinum neurotoxin D-C. | 22454523 |
| 2012-04-14 10:48:00 | synaptotagmin-II is not a high affinity receptor for BoNT/B and G due to a phenylalanine to leucine mutation in its luminal domain present only in humans and chimpanzees | 22265973 |
| Type | IDs |
|---|---|
| Synonymous | CMS7, MYSPC, SytII |
| Gene |
UniProtKB-ID:
SYT2_HUMAN
UniprotKB:
Q8N9I0
UniParc:
UPI000006E8FC
EMBL:
BC100817,
AK094430,
BC100815,
BC100814,
AK090672
Ensembl:
ENSG00000143858
KO:
hsa:127833
|
| Nucleutide sequences |
EMBL-CDS:
BAC03500.1,
AAI00816.1,
BAC04354.1,
AAI00815.1,
AAI00818.1
Ensembl_TRS:
ENST00000367267,
ENST00000367268
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000356236,
ENSP00000356237
RefSeq:
XP_011507494.1,
XP_016855798.1,
XP_016855799.1,
XP_016855800.1,
NP_796376.2,
XP_016855802.1,
XP_016855801.1,
NP_001129976.1
|
| Others |
UniRef100:
UniRef100_Q8N9I0
UniRef90:
UniRef90_Q8N9I0
UniRef50:
UniRef50_P21707
UniGene:
Hs.25422
CCDS:
CCDS1427.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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