| Type | Description |
|---|---|
| Definition | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-19 13:42:00 | Reduced Mrp2 surface availability as PI3Kgamma-mediated hepatocytic dysfunction reflecting a hallmark of cholestasis in sepsis. | 32753644 |
| 2018-11-24 11:38:00 | The authors conclude that MRP1 assists in depression of polymorphonuclear cell migration by effluxing a molecule that inhibits the proinflammatory effects of MRP2 activity. | 29976647 |
| 2018-05-05 11:13:00 | Circadian oscillation of Mrp2 protein expression was clearly observed in the mouse liver with levels down at the light phase and up at the dark phase. | 28479363 |
| 2017-06-10 12:28:00 | Biotinylation and streptavidin pull-down assays confirmed that CAL dramatically reduces the expression level of total and cell surface Mrp2 in Huh-7 cells. Our findings suggest that CAL interacts with Mrp2 and is a negative regulator of Mrp2 expression. | 27834195 |
| 2014-12-20 11:11:00 | Deficiency in Mrp2 lowers platinum excretion and increases susceptibility to kidney injury, which can be rescued by the human MRP2 ortholog. | 24641901 |
| Type | IDs |
|---|---|
| Synonymous | AI173996, Abc30, Cmoat, Mrp2, cMRP |
| Gene |
UniProtKB-ID:
MRP2_MOUSE
UniprotKB:
Q8VI47
UniParc:
UPI000002256A
EMBL:
AF282772,
AF282773
Ensembl:
ENSMUSG00000025194
KO:
mmu:12780
|
| Nucleutide sequences |
EMBL-CDS:
AAL36985.1,
AAL36986.1
Ensembl_TRS:
ENSMUST00000026208
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000026208
RefSeq:
NP_038834.2,
XP_006526688.1
|
| Others |
UniRef100:
UniRef100_Q8VI47
UniRef90:
UniRef90_Q8VI47
UniRef50:
UniRef50_Q92887
UniGene:
Mm.39054
CCDS:
CCDS29838.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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