| Type | Description |
|---|---|
| Definition | chemokine (C-C motif) receptor 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-15 19:03:00 | Chemokine receptor 3 is a negative regulator of trabecular bone mass in female mice. | 30977156 |
| 2019-10-26 12:16:00 | CD193(+) neutrophils increase in number under inflammatory conditions due to chronic IL-21 production. | 29778007 |
| 2019-01-12 10:08:00 | CCR3 gene knockout may alleviate Eosinophil (EOS) invasion and the inflammatory response in allergic rhinitis model mice by reducing the expression levels of EOS peroxidase, EOS cationic protein, major basic protein, IL4, and IgE, and increasing the expression of IL10 and IFNgamma. | 30106146 |
| 2017-12-30 12:41:00 | We found abnormalities in sleep patterns in the resting phase and in the number of Hcrt neurons in Ccr3 KO mice. These observations suggest a role for CCR3 in sleep-wake regulation in narcolepsy patients | 29186205 |
| 2017-10-28 10:57:00 | Study found that CCR3 plays a crucial role in neuronal injury. CCR3 deletion or inhibition protects neurons from oxygen-glucose-deprivation-induced cytotoxicity in primary cortical cultures. CCR3 KO mice also displayed significant reduction of infarct volume in the brain after experimental stroke. | 27822494 |
| Type | IDs |
|---|---|
| Synonymous | CC-CKR3, CKR3, Cmkbr1l2, Cmkbr3 |
| Gene |
UniProtKB-ID:
CCR3_MOUSE,
Q3U5L7_MOUSE
UniprotKB:
P51678,
Q3U5L7
UniParc:
UPI00000249AB,
UPI00005ACCD0
EMBL:
U29677,
AK041106,
AK153518,
U28406,
CH466671,
BC108967,
BC108968,
AY049018
Ensembl:
ENSMUSG00000035448
KO:
mmu:12771
|
| Nucleutide sequences |
EMBL-CDS:
AAI08969.1,
AAL13085.1,
AAA89155.1,
AAA86118.1,
AAI08968.1,
EDL37175.1,
BAC30823.1,
BAE32061.1
Ensembl_TRS:
ENSMUST00000039171
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000039107
RefSeq:
XP_017168608.1,
NP_034044.3
|
| Others |
UniRef100:
UniRef100_Q3U5L7,
UniRef100_P51678
UniRef90:
UniRef90_P51678
UniRef50:
UniRef50_P32246
UniGene:
Mm.57050
CCDS:
CCDS23668.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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