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12764 Cmas

12764

Cmas

cytidine monophospho-N-acetylneuraminic acid synthetase

protein-coding

Mus musculus

基因描述

Type Description
Definition cytidine monophospho-N-acetylneuraminic acid synthetase

研究结论

Date Results Publications
2021-03-20 13:33:00 Cytidine Monophosphate N-Acetylneuraminic Acid Synthetase and Solute Carrier Family 35 Member A1 Are Required for Reovirus Binding and Infection. 33087464
2019-08-10 12:20:00 CRISPR/Cas9-mediated knock out of the CMAS gene, encoding a key enzyme in the sialylation pathway, in the mouse colorectal cancer MC38 cell line completely abrogated cell surface expression of sialic acids (MC38-Sia(null) ) and, unexpectedly, significantly increased in vivo tumor growth compared to the control MC38-MOCK cells. 30578646
2017-07-15 10:46:00 Sialylation is dispensable for early murine embryonic development in vitro in CMAS-null embryonic stem cells. 28374933
2010-01-25 12:49:00 The authors provide evidence that the C-terminal domain of CMP-Sialic Acid Synthetase (CSS) serves as a platform for the quaternary organization governing the kinetic properties of the physiologically active enzyme as demonstrated in kinetic studies.[CSS] 19666032
2010-01-21 00:00:00 Nuclear localization signal of murine CMP-Neu5Ac synthetase includes residues required for both nuclear targeting and enzymatic activity 11893746

名称对应

Type IDs
Synonymous AW208911, CMPNeu5Ac, D6Bwg0250e
Gene
UniProtKB-ID: NEUA_MOUSE, A0A0R4J0B4_MOUSE
UniprotKB: Q99KK2, A0A0R4J0B4
UniParc: UPI00000286B0, UPI00000E5990, UPI00000E9F9C
EMBL: AK087150, BC063776, AC164104, BC031500, BC004606, AJ006215
Ensembl: ENSMUSG00000030282
KO: mmu:12764
Nucleutide sequences
EMBL-CDS: AAH31500.1, AAH04606.1, CAA06915.1, AAH63776.1, BAC39813.1
Ensembl_TRS: ENSMUST00000032419
Protein sequencees
Ensembl_PRO: ENSMUSP00000032419
RefSeq: NP_034038.2, XP_030110994.1
Others
UniRef100: UniRef100_A0A0R4J0B4, UniRef100_Q99KK2
UniRef90: UniRef90_Q99KK2
UniRef50: UniRef50_Q99KK2
UniGene: Mm.3820
CCDS: CCDS20687.1

全选

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